Colchicine

Category: Phytochemicals

Synonyms: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; 64-86-8
CAS-Number: C₂₂H₂₅NO₆
Molecular Formula: 399.44
Molecular Weight

Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.
Long Term Storage: +4°C
Short Term Storage: +4°C
Shipping: AMBIENT

Description: Binds specifically with tubulin thus interfering with microtubule organization.
InChi: InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
References: (1) P. Dustin et al.: Microtubles Berlin, 11, (1978)
InChi Key: IAKHMKGGTNLKSZ-UHFFFAOYSA-N
Smiles: COC1=C(OC)C(OC)=C2C(CCC(NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1

Binds specifically with tubulin thus interfering with microtubule organization.

SKU: C0032 Category: Phytochemicals

Additional information

Synonyms	(S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
Purity	≥95% (HPLC)
Appearance	Yellow or off-white crystalline powder
CAS-Number	64-86-8
Molecular Formula	C22H25NO6
Molecular Weight	399.44
Identity	1H-NMR
Solvents	chloroform, ethanol (50 mg/ml)
Melting Point	150-160 °C
Smiles	COC1=C(OC)C(OC)=C2C(CCC(NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
InChi Key	IAKHMKGGTNLKSZ-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H300 H330-H318- H340
Precautionary statements	P201, P260, P264, P280-P284-P301 + P310
GHS Symbol	GHS05+GHS06+GHS08
Signal word	Danger
RIDADR	UN1544 6.1
Transportation	Excepted Quantities
References	(1) P. Dustin et al.: Microtubles Berlin, 11, (1978)
InChi	InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
Quantity	100 mg, 5 g, 50 g, Bulk