Specifications
- Purity
- ≥98% (HPLC)
- Identity
- 1H-NMR
- Appearance
- Reddish-violet liquid
Properties
- Boiling Point
- 219°C
- Melting Point
- 219°C
- Solvents
- DMSO
Available from stock
DAR-4M solution (5 mM in DMSO), 1 mg in 0.46 ml DMSO
- SKU
- D0506
Category: Fluorescent Detection
- Synonyms
- Diaminorhodamine-4M , 3,6-Bis(dimethylamino)-9-[3-amino-4-(N-methylamino)-2-carboxyphenyl]xanthylium
- 339527-79-6
- CAS-Number
- C25H26N4O3
- Molecular Formula
- 430.51
- Molecular Weight
- Long Term Storage
- -20°C
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Handling Advice
- Protect from light and moisture.
- Short Term Storage
- +4°C
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Signal word
- Warning
- GHS Symbol
- GHS07
- Precautionary statements
- P261-P305 + P351 + P338
- Hazard statements
- H315-H319-H335
- Description
- Photo-stable fluorescent probe (Ex: ~560nm, Em: 575nm) for the detection of nitric oxide (NO) in presence of oxygen, resulting in a triazolo-rhodamine analog (DAR-4M T) that exhibits about 840-fold greater fluorescence quantum efficiency. Suitable probe for monitoring RNS production, but not NO alone. Stable in a pH range of 4-12. Detection limit ~10nM.
- InChi
- InChI=1S/C25H26N4O3/c1-27-19-11-10-18(23(24(19)26)25(30)31)22-16-8-6-14(28(2)3)12-20(16)32-21-13-15(29(4)5)7-9-17(21)22/h6-13,27H,26H2,1-5H3
- References
- (1) H. Kojima, et al., Anal. Chem.73, 1967 (2001) , (2) H. Kojima & N. Nagano, Advanced Materials 12, 763 (2000) , (3) H. Kojima, et al., Tetrahedr. Lett. 41, 69 (2000) , (4) Z. Lacza, et al., J. Pharmacol. Toxicol. Meth. 52, 335 (2005)
- InChi Key
- LNDSYTUQQCXPAM-UHFFFAOYSA-N
- Smiles
- CN(C)C1=CC2=[O+]C(C=C(N(C)C)C=C3)=C3C(C4=CC=C(NC)C(N)=C4C([O-])=O)=C2C=C1
Photo-stable fluorescent probe (Ex: ~560nm, Em: 575nm) for the detection of nitric oxide (NO) in presence of oxygen, resulting in a triazolo-rhodamine analog (DAR-4M T) that exhibits about 840-fold greater fluorescence quantum efficiency. Suitable probe for monitoring RNS production, but not NO alone. Stable in a pH range of 4-12. Detection limit ~10nM.
Additional information
| Synonyms | Diaminorhodamine-4M, 3,6-Bis(dimethylamino)-9-[3-amino-4-(N-methylamino)-2-carboxyphenyl]xanthylium |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | Reddish-violet liquid |
| CAS-Number | 339527-79-6 |
| Molecular Formula | C25H26N4O3 |
| Molecular Weight | 430.51 |
| Identity | 1H-NMR |
| Solvents | DMSO |
| Melting Point | 219°C |
| Boiling Point | 219°C |
| Smiles | CN(C)C1=CC2=[O+]C(C=C(N(C)C)C=C3)=C3C(C4=CC=C(NC)C(N)=C4C([O-])=O)=C2C=C1 |
| InChi Key | LNDSYTUQQCXPAM-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) H. Kojima, et al., Anal. Chem.73, 1967 (2001), (2) H. Kojima & N. Nagano, Advanced Materials 12, 763 (2000), (3) H. Kojima, et al., Tetrahedr. Lett. 41, 69 (2000), (4) Z. Lacza, et al., J. Pharmacol. Toxicol. Meth. 52, 335 (2005) |
| InChi | InChI=1S/C25H26N4O3/c1-27-19-11-10-18(23(24(19)26)25(30)31)22-16-8-6-14(28(2)3)12-20(16)32-21-13-15(29(4)5)7-9-17(21)22/h6-13,27H,26H2,1-5H3 |
| Quantity | 1 mg, Bulk |
