3,8-Diamino-6-phenylphenanthridine

SKU: D0436

Category: Fluorescent Detection

Synonyms: 6-Phenylphenathridine-3,8-diamine , 3,8-DAPP , DAPP; 52009-64-0
CAS-Number: C₁₉H₁₅N₃
Molecular Formula: 285.34
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Identity: 1H-NMR
Appearance: Yellow to orange powder

Properties

Melting Point: 195-198°C
Solvents: chloroform, dichloromethane, methanol

Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
Long Term Storage: -20°C
Short Term Storage: +4°C
Shipping: AMBIENT

Transportation: Not dangerous goods
Signal word: Warning
GHS Symbol: GHS07
Precautionary statements: P261-P305 + P351 + P338
Hazard statements: H302-H315-H319-H335

Description: Phenyl-phenanthridine dye with a large ?-conjugated structure and strong luminescence. Used in the synthesis of rigid polyamides and fluorescent probes. DNA intercalator. Used as a chromatographic affinity ligand for the specific separation and purification of supercoiled plasmid DNA (pDNA). It has been investigated for its anti-tumor and anti-viral properties.
InChi: InChI=1S/C19H15N3/c20-13-6-8-15-16-9-7-14(21)11-18(16)22-19(17(15)10-13)12-4-2-1-3-5-12/h1-11H,20-21H2
References: (1) A.L. Cimecioglu & R.A. Weiss , Macromolecules 28, 6343 (1995) , (2) V.K. Misra & B. Honig , PNAS 92, 4691 (1995) , (3) T. Kubar, et al. , Chem. Eur. J. 12, 280 (2006) , (4) X. Shi & R.B. MacGregor Jr. , J. Phys. Chem. B. 111, 3321 (2007) , (5) S.A. Osadchiia, et al. , Russ. J. Appl. Chem. 84, 1541 (2011) , (6) C. Caramelo-Nunes, et al. , J.Chromatogr. A 1307, 91 (2013) , (7) C. Caramelo-Nunes, et al. , Meth. Mol. Biol. 1286, 47 (2015)
InChi Key: CPNAVTYCORRLMH-UHFFFAOYSA-N
Smiles: NC1=CC2=C(C(C=CC(N)=C3)=C3N=C2C4=CC=CC=C4)C=C1

Phenyl-phenanthridine dye with a large ?-conjugated structure and strong luminescence. Used in the synthesis of rigid polyamides and fluorescent probes. DNA intercalator. Used as a chromatographic affinity ligand for the specific separation and purification of supercoiled plasmid DNA (pDNA). It has been investigated for its anti-tumor and anti-viral properties.

SKU: D0436 Category: Fluorescent Detection

Additional information

Additional information

Synonyms	6-Phenylphenathridine-3,8-diamine, 3,8-DAPP, DAPP
Purity	≥98% (HPLC)
Appearance	Yellow to orange powder
CAS-Number	52009-64-0
Molecular Formula	C19H15N3
Molecular Weight	285.34
Identity	1H-NMR
Solvents	chloroform, dichloromethane, methanol
Melting Point	195-198°C
Smiles	NC1=CC2=C(C(C=CC(N)=C3)=C3N=C2C4=CC=CC=C4)C=C1
InChi Key	CPNAVTYCORRLMH-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305 + P351 + P338
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) A.L. Cimecioglu & R.A. Weiss, Macromolecules 28, 6343 (1995), (2) V.K. Misra & B. Honig, PNAS 92, 4691 (1995), (3) T. Kubar, et al., Chem. Eur. J. 12, 280 (2006), (4) X. Shi & R.B. MacGregor Jr., J. Phys. Chem. B. 111, 3321 (2007), (5) S.A. Osadchiia, et al., Russ. J. Appl. Chem. 84, 1541 (2011), (6) C. Caramelo-Nunes, et al., J.Chromatogr. A 1307, 91 (2013), (7) C. Caramelo-Nunes, et al., Meth. Mol. Biol. 1286, 47 (2015)
InChi	InChI=1S/C19H15N3/c20-13-6-8-15-16-9-7-14(21)11-18(16)22-19(17(15)10-13)12-4-2-1-3-5-12/h1-11H,20-21H2
Quantity	1 g, 5 g, Bulk