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      3,8-Diamino-6-phenylphenanthridine

      SKU
      D0436

      Category: Fluorescent Detection

      Synonyms
      6-Phenylphenathridine-3,8-diamine , 3,8-DAPP , DAPP
      52009-64-0
      CAS-Number
      C19H15N3
      Molecular Formula
      285.34
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (HPLC)
      Identity
      1H-NMR
      Appearance
      Yellow to orange powder

      Properties

      Melting Point
      195-198°C
      Solvents
      chloroform, dichloromethane, methanol

      Downloads

      Safety Data Sheet
      CDX D0436 MSDS.pdf
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Long Term Storage
      -20°C
      Short Term Storage
      +4°C
      Shipping
      AMBIENT
      Transportation
      Not dangerous goods
      Signal word
      Warning
      GHS Symbol
      GHS07
      Precautionary statements
      P261-P305 + P351 + P338
      Hazard statements
      H302-H315-H319-H335
      Description
      Phenyl-phenanthridine dye with a large ?-conjugated structure and strong luminescence. Used in the synthesis of rigid polyamides and fluorescent probes. DNA intercalator. Used as a chromatographic affinity ligand for the specific separation and purification of supercoiled plasmid DNA (pDNA). It has been investigated for its anti-tumor and anti-viral properties.
      InChi
      InChI=1S/C19H15N3/c20-13-6-8-15-16-9-7-14(21)11-18(16)22-19(17(15)10-13)12-4-2-1-3-5-12/h1-11H,20-21H2
      References
      (1) A.L. Cimecioglu & R.A. Weiss , Macromolecules 28, 6343 (1995) , (2) V.K. Misra & B. Honig , PNAS 92, 4691 (1995) , (3) T. Kubar, et al. , Chem. Eur. J. 12, 280 (2006) , (4) X. Shi & R.B. MacGregor Jr. , J. Phys. Chem. B. 111, 3321 (2007) , (5) S.A. Osadchiia, et al. , Russ. J. Appl. Chem. 84, 1541 (2011) , (6) C. Caramelo-Nunes, et al. , J.Chromatogr. A 1307, 91 (2013) , (7) C. Caramelo-Nunes, et al. , Meth. Mol. Biol. 1286, 47 (2015)
      InChi Key
      CPNAVTYCORRLMH-UHFFFAOYSA-N
      Smiles
      NC1=CC2=C(C(C=CC(N)=C3)=C3N=C2C4=CC=CC=C4)C=C1

      Phenyl-phenanthridine dye with a large ?-conjugated structure and strong luminescence. Used in the synthesis of rigid polyamides and fluorescent probes. DNA intercalator. Used as a chromatographic affinity ligand for the specific separation and purification of supercoiled plasmid DNA (pDNA). It has been investigated for its anti-tumor and anti-viral properties.

      SKU: D0436 Category: Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      6-Phenylphenathridine-3,8-diamine, 3,8-DAPP, DAPP

      Purity

      ≥98% (HPLC)

      Appearance

      Yellow to orange powder

      CAS-Number

      52009-64-0

      Molecular Formula

      C19H15N3

      Molecular Weight

      285.34

      Identity

      1H-NMR

      Solvents

      chloroform, dichloromethane, methanol

      Melting Point

      195-198°C

      Smiles

      NC1=CC2=C(C(C=CC(N)=C3)=C3N=C2C4=CC=CC=C4)C=C1

      InChi Key

      CPNAVTYCORRLMH-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H302-H315-H319-H335

      Precautionary statements

      P261-P305 + P351 + P338

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) A.L. Cimecioglu & R.A. Weiss, Macromolecules 28, 6343 (1995), (2) V.K. Misra & B. Honig, PNAS 92, 4691 (1995), (3) T. Kubar, et al., Chem. Eur. J. 12, 280 (2006), (4) X. Shi & R.B. MacGregor Jr., J. Phys. Chem. B. 111, 3321 (2007), (5) S.A. Osadchiia, et al., Russ. J. Appl. Chem. 84, 1541 (2011), (6) C. Caramelo-Nunes, et al., J.Chromatogr. A 1307, 91 (2013), (7) C. Caramelo-Nunes, et al., Meth. Mol. Biol. 1286, 47 (2015)

      InChi

      InChI=1S/C19H15N3/c20-13-6-8-15-16-9-7-14(21)11-18(16)22-19(17(15)10-13)12-4-2-1-3-5-12/h1-11H,20-21H2

      Quantity

      1 g, 5 g, Bulk

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