Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- water (20 mg/ml), ethanol (20mg/ml), DMSO and DMF (30mg/ml)
Documentation
- Safety Data Sheet (SDS)
- CDX A0222 MSDS.pdf
Available from stock
L-Alanyl-L-glutamine
- SKU
- A0222
Category: Amino Acids, Peptides, Proteins
- Synonyms
- H-Ala-Gln-OH , Ala-Gln , L-Ala L-Gln , Alanyl-glutamine , Glutamine-S
- 39537-23-0
- CAS-Number
- C8H15N3O4
- Molecular Formula
- 217.22
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- RT
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at RT.
- Transportation
- Not dangerous goods
- Description
- L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture media as alternative delivery forms of stabilized L-glutamine. Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals, cosmetics and food products. Alanyl-glutamine also acts as an antioxidant (peroxide) and anti-apoptosis (LPS-induced) factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro. Shown to improve intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy. It improves pancreatic beta-cell function, maintaining the mitochondrial metabolism and stimulus-secretion coupling essential for insulin release.
- Smiles
- NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
- InChi Key
- HJCMDXDYPOUFDY-WHFBIAKZSA-N
- References
- (1) P.G. Boelens, et al., Am. J. Physiol. Endocrinol. Metab. 291, E683 (2006) , (2) Y. Imamoto, et al., Cytotechnology 65, 135 (2013) , (3) E.R. Petry, et al., Life Sci. 94, 130 (2014) , (4) V.F. Cruzat, et al., Nutrition 30, 602 (2014) , (5) M.V. Nova, et al., Drug Dev. Ind. Pharm. 40, 1308 (2014) , (6) G. Wang, et al., Ind. Eng. Chem. Res. 53, 3385 (2014) , (7) V.F. Cruzat, et al., J. Endocrinol. 224, 261 (2015)
L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture media as alternative delivery forms of stabilized L-glutamine. Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals, cosmetics and food products. Alanyl-glutamine also acts as an antioxidant (peroxide) and anti-apoptosis (LPS-induced) factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro. Shown to improve intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy. It improves pancreatic beta-cell function, maintaining the mitochondrial metabolism and stimulus-secretion coupling essential for insulin release.
Additional information
| Synonyms | H-Ala-Gln-OH, Ala-Gln, L-Ala L-Gln, Alanyl-glutamine, Glutamine-S |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder |
| CAS-Number | 39537-23-0 |
| Molecular Formula | C8H15N3O4 |
| Molecular Weight | 217.22 |
| Identity | 1H-NMR |
| Solvents | water (20 mg/ml), ethanol (20mg/ml), DMSO and DMF (30mg/ml) |
| Smiles | NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O |
| InChi Key | HJCMDXDYPOUFDY-WHFBIAKZSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | RT |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
| Transportation | Not dangerous goods |
| References | (1) P.G. Boelens, et al., Am. J. Physiol. Endocrinol. Metab. 291, E683 (2006), (2) Y. Imamoto, et al., Cytotechnology 65, 135 (2013), (3) E.R. Petry, et al., Life Sci. 94, 130 (2014), (4) V.F. Cruzat, et al., Nutrition 30, 602 (2014), (5) M.V. Nova, et al., Drug Dev. Ind. Pharm. 40, 1308 (2014), (6) G. Wang, et al., Ind. Eng. Chem. Res. 53, 3385 (2014), (7) V.F. Cruzat, et al., J. Endocrinol. 224, 261 (2015) |
| Quantity | 10 g, 50 g, Bulk |
