Specifications
- Purity
- ≥97% (T)
- Appearance
- White to light grey to brown powder
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in DMSO or chloroform.
- Melting Point
- 64-67 °C (lit.)
Category: Building Blocks, Intermediates, Reagents
Methanesulfonic anhydride is a building block for organic synthesis. It is used to prepare methylsulfonyl esters, also called as mesylates. It finds application in the reaction of aromatic alkylation. It reacts with dimethylsulfoxide to get sulfoxonium complex, which is a useful oxidizing agent. It is a more powerful sulfonylating reagent than the sulfonyl chloride. Used in the synthesis of (R)-Amino Carnitine, an inhibitor of fatty acid oxidation.
Synonyms | Mesyl anhydride, Ms2O, NSC65906 |
---|---|
Purity | ≥97% (T) |
Appearance | White to light grey to brown powder |
CAS-Number | 7143-01-3 |
Molecular Formula | C2H6O5S2 |
Molecular Weight | 174.20 |
Identity | 1H-NMR |
Solvents | Soluble in DMSO or chloroform. |
Melting Point | 64-67 °C (lit.) |
Smiles | CS(=O)(OS(=O)(C)=O)=O |
InChi Key | IZDROVVXIHRYMH-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
Hazard statements | H314 |
Precautionary statements | P280 – P305 + P351 + P338 – P310 |
GHS Symbol | GHS05 |
Signal word | Danger |
RIDADR | UN3261 |
Transportation | Packing Group II |
References | [1] K. Smith, et al., Org. Biomol. Chem. 2, 3150 (2004), [2] M.C. Wilkinson, Org. Lett. 13, 2232 (2011), [3] W. Liu, & T.D. Tilley, Langmuir 31, 1189 (2015), [4] Y. Hu, et al., Med. Chem. 5, 354 (2015), [5] M. Hasani, et al., J. Phys. Chem. B, 123, 1815 (2019) |
InChi | InChI=1S/C2H6O5S2/c1-8(3,4)7-9(2,5)6/h1-2H3 |
Quantity | 10 g, 50 g, Bulk |