Specifications
- Purity
- ≥97% (NMR)
- Appearance
- Yellow to orange powder
- Identity
- 1H-NMR
Properties
- Solvents
- Slightly methanol (1 mg/ml)
- Fluorescence
- λex 360 nm, λem 530 nm±10 nm in methanol
Documentation
- Safety Data Sheet (SDS)
- CDX C0068 MSDS.pdf
Available from stock
N-Dansylethylenediamine
- SKU
- C0068
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- N-Dansylethylenediamine , N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide , N-(2-Aminoethyl)dansylamide , DNSEDA , NSC 666752 , Dansyl EDA
- 35060-08-3
- CAS-Number
- C14H19N3O2S
- Molecular Formula
- 293.38
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- -20°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: λex=335nm, λem=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner.
- Smiles
- CN(C)C1=C(C=CC=C2S(=O)(NCCN)=O)C2=CC=C1
- InChi Key
- CSJXLKVNKAXFSI-UHFFFAOYSA-N
- References
- (1) H. Adachi, et al., Biochim. Biophys. Acta 1163, 42 (1993) , (2) A. Sonoki, et al., J. Liqu. Chrom. Rel. Technol. 17, 1057 (1994) , (3) J. Moraczewska, et al., Biophys J. 77, 373 (1999) , (4) L. Prodi, et al., Hel. Chim. Acta 84, 690 (2001) , (5) S. Mallampati, et al., Electrophoresis 28, 3948 (2007) , (6) R.W. Dudley, et al., Mol. Cell Biochem. 346, 81 (2011) , (7) Y. Inoue, et al., Biosens. Bioelectron. 48, 113 (2013)
- InChi
- InChI=1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3
Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: λex=335nm, λem=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner.
Additional information
| Synonyms | N-Dansylethylenediamine, N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide, N-(2-Aminoethyl)dansylamide, DNSEDA, NSC 666752, Dansyl EDA |
|---|---|
| Purity | ≥97% (NMR) |
| Appearance | Yellow to orange powder |
| CAS-Number | 35060-08-3 |
| Molecular Formula | C14H19N3O2S |
| Molecular Weight | 293.38 |
| Identity | 1H-NMR |
| Solvents | Slightly methanol (1 mg/ml) |
| Fluorescence | λex 360 nm, λem 530 nm±10 nm in methanol |
| Smiles | CN(C)C1=C(C=CC=C2S(=O)(NCCN)=O)C2=CC=C1 |
| InChi Key | CSJXLKVNKAXFSI-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) H. Adachi, et al., Biochim. Biophys. Acta 1163, 42 (1993), (2) A. Sonoki, et al., J. Liqu. Chrom. Rel. Technol. 17, 1057 (1994), (3) J. Moraczewska, et al., Biophys J. 77, 373 (1999), (4) L. Prodi, et al., Hel. Chim. Acta 84, 690 (2001), (5) S. Mallampati, et al., Electrophoresis 28, 3948 (2007), (6) R.W. Dudley, et al., Mol. Cell Biochem. 346, 81 (2011), (7) Y. Inoue, et al., Biosens. Bioelectron. 48, 113 (2013) |
| InChi | InChI=1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3 |
| Quantity | 500 mg, 1 g, Bulk |
