Available from stock

Neohesperidin dihydrochalcone

SKU: N0157

Category: Carbohydrates

Synonyms: NHDC , Neohesperidin DC , Neohesperidin DHC , 1-(4-((2-O-[6-Deoxy-&alpha , -L-mannopyranosyl]-β-D-glucopyranosyl)oxy)-2,6-dihydroxyphenyl)-3-[3-hydroxy-4-methoxyphenyl]-1-propanone; 20702-77-6
CAS-Number: C₂₈H₃₆O₁₅
Molecular Formula: 612.58
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥97% (HPLC)
Appearance: Off-white powder
Identity: 1H-NMR

Properties

Solvents: methanol
Melting Point: 156-158 °C (lit.)

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Transportation: Not dangerous goods

Description: Neohesperidin dihydrochalcone is a flavonoid sweetening agent with potent antioxidant activity. It is a preparation from Naringen, a flavanone glycoside occurring naturally in grapefruit. It is used as an artifical sweetener, especially in chewing gum and dentifrices. In food it is used as a flavour enhancer in concentrations of around 4-5 parts per million (ppm) and as an artificial sweetener at around 15-20 ppm. Pharmaceutical companies use it reducing the bitterness of pharmacological drugs in tablet form, and it has been used for livestock feed as a means of reducing feeding time. It is also widely favoured for use in otherwise naturally bitter products. As a flavour enhancer, NHDC is used in a wide range of products and is indicated by the E number E 959. It is noted particularly for enhancing sensory effects.
Smiles: COC1=CC=C(C=C1O)CCC(C2=C(C=C(C=C2O)O[C@@H]([C@@H]3O[C@@H]([C@@H]4O)O[C@H]([C@@H]([C@H]4O)O)C)O[C@@H]([C@H]([C@@H]3O)O)CO)O)=O
InChi Key: ITVGXXMINPYUHD-CUVHLRMHSA-N
References: (1) G.E. Inglett, et al.: J. Food Sci. 34, 101 (1969) , (2) J.F. Fisher, J. Agric. Food Chem. 25, 682 (1977) , (3) P.J. Pratter, Perfum. Flavor. 5, 12 (1981) , (4) B.A.R. Lina, et al., Food Chem. Toxicol. 28, 507 (1990) , (5) J.-M. Choi, et al., Biol. Pharm. Bull. 30, 324 (2007)

Neohesperidin dihydrochalcone is a flavonoid sweetening agent with potent antioxidant activity. It is a preparation from Naringen, a flavanone glycoside occurring naturally in grapefruit. It is used as an artifical sweetener, especially in chewing gum and dentifrices. In food it is used as a flavour enhancer in concentrations of around 4-5 parts per million (ppm) and as an artificial sweetener at around 15-20 ppm. Pharmaceutical companies use it reducing the bitterness of pharmacological drugs in tablet form, and it has been used for livestock feed as a means of reducing feeding time. It is also widely favoured for use in otherwise naturally bitter products. As a flavour enhancer, NHDC is used in a wide range of products and is indicated by the E number E 959. It is noted particularly for enhancing sensory effects.

SKU: N0157 Category: Carbohydrates

Additional information

Additional information

Synonyms	NHDC, Neohesperidin DC, Neohesperidin DHC, 1-(4-((2-O-[6-Deoxy-&alpha, -L-mannopyranosyl]-β-D-glucopyranosyl)oxy)-2,6-dihydroxyphenyl)-3-[3-hydroxy-4-methoxyphenyl]-1-propanone
Purity	≥97% (HPLC)
Appearance	Off-white powder
CAS-Number	20702-77-6
Molecular Formula	C28H36O15
Molecular Weight	612.58
Identity	1H-NMR
Solvents	methanol
Melting Point	156-158 °C (lit.)
Smiles	COC1=CC=C(C=C1O)CCC(C2=C(C=C(C=C2O)O[C@@H]([C@@H]3O[C@@H]([C@@H]4O)O[C@H]([C@@H]([C@H]4O)O)C)O[C@@H]([C@H]([C@@H]3O)O)CO)O)=O
InChi Key	ITVGXXMINPYUHD-CUVHLRMHSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	(1) G.E. Inglett, et al.: J. Food Sci. 34, 101 (1969), (2) J.F. Fisher, J. Agric. Food Chem. 25, 682 (1977), (3) P.J. Pratter, Perfum. Flavor. 5, 12 (1981), (4) B.A.R. Lina, et al., Food Chem. Toxicol. 28, 507 (1990), (5) J.-M. Choi, et al., Biol. Pharm. Bull. 30, 324 (2007)
Quantity	1 g, 5 g, Bulk