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    Phenol red sodium salt

    Available from stock

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      Phenol red sodium salt

      SKU
      P0026

      Category: Non Fluorescent Detection & Chromogene Detection

      Synonyms
      4,4'-(1,1-Dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-phenol sodium salt , Phenolsulfonephthalein sodium salt
      34487-61-1
      CAS-Number
      C19H13O5S . Na
      Molecular Formula
      376.36
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      Dye content 90% (Titration)
      Identity
      1H-NMR
      Appearance
      Red to brown powder

      Properties

      Solvents
      water (1 mg/ml)

      Downloads

      Safety Data Sheet
      CDX P0026 MSDS.pdf
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at RT.
      Long Term Storage
      RT
      Short Term Storage
      RT
      Shipping
      AMBIENT
      Transportation
      Packing Group III
      Signal word
      Warning
      GHS Symbol
      GHS07
      Precautionary statements
      P261-P305 + P351 + P338
      Hazard statements
      H315-H319-H335
      Description
      Water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range and frequently used in cell biology laboratories. Widely used as cell tissue culture pH marker. A small amount of phenol red added to the growth medium will have a pink-red color under normal conditions. Typically, 15 mg/l are used for cell culture. In the event of problems, waste products produced by dying cells or overgrowth of contaminants will cause a change in pH, leading to a change in indicator color. For example, a culture of relatively slowly dividing mammalian cells can be quickly overgrown by bacterial contamination. This usually results in an acidification of the medium, turning it yellow. The waste products produced by the mammalian cells themselves will slowly decrease the pH, gradually turning the solution orange and then yellow. This color change is an indication that even in the absence of contamination, the medium needs to be replaced. Shown to be a weak estrogen mimic (possible through inpurities), which can enhance the growth of cells that express the estrogen receptor in cell cultures. Might be useful as a differentiation factor.
      InChi
      InChI=1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
      References
      (1) F.L. Rodkey: Arch. Biochem. Biophys. 94, 38 (1961) , (2) T. Hoshi & H. Hayashi: Jpn. J. Physiol. 20, 683 (1970) , (3) U. Kragh-Hansen & J.V. Moller: Biochim. Biophys. Acta 295, 438 (1973) , (4) Y. Berthois, et al.: PNAS 83, 2496 (1986) , (5) P. Yuan & D.R. Walt: J. Fluoresc. 2, 231 (1992) , (6) L. Hopp & C.H. Bunker: J. Cell Physiol. 157, 594 (1993) , (7) J. Wesierska-Gadek, et al.: Cell Mol. Biol. Lett. 12, 280 (2007) , (8) H. Lysdahl, et al.: Stem Cell Rev. 9, 132 (2013)
      InChi Key
      BELBBZDIHDAJOR-UHFFFAOYSA-N
      Smiles
      O=S1(C2=CC=CC=C2C(C3=CC=C(O)C=C3)(C4=CC=C(O)C=C4)O1)=O

      Water soluble pH indicator used in the 6.8 (yellow) to 8.2 (red) range and frequently used in cell biology laboratories. Widely used as cell tissue culture pH marker. A small amount of phenol red added to the growth medium will have a pink-red color under normal conditions. Typically, 15 mg/l are used for cell culture. In the event of problems, waste products produced by dying cells or overgrowth of contaminants will cause a change in pH, leading to a change in indicator color. For example, a culture of relatively slowly dividing mammalian cells can be quickly overgrown by bacterial contamination. This usually results in an acidification of the medium, turning it yellow. The waste products produced by the mammalian cells themselves will slowly decrease the pH, gradually turning the solution orange and then yellow. This color change is an indication that even in the absence of contamination, the medium needs to be replaced. Shown to be a weak estrogen mimic (possible through inpurities), which can enhance the growth of cells that express the estrogen receptor in cell cultures. Might be useful as a differentiation factor.

      SKU: P0026 Category: Non Fluorescent Detection & Chromogene Detection
      • Additional information

      Additional information

      Synonyms

      4,4'-(1,1-Dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-phenol sodium salt, Phenolsulfonephthalein sodium salt

      Purity

      Dye content 90% (Titration)

      Appearance

      Red to brown powder

      CAS-Number

      34487-61-1

      Molecular Formula

      C19H13O5S . Na

      Molecular Weight

      376.36

      Identity

      1H-NMR

      Solvents

      water (1 mg/ml)

      Smiles

      O=S1(C2=CC=CC=C2C(C3=CC=C(O)C=C3)(C4=CC=C(O)C=C4)O1)=O

      InChi Key

      BELBBZDIHDAJOR-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      RT

      Long Term Storage

      RT

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at RT.

      Hazard statements

      H315-H319-H335

      Precautionary statements

      P261-P305 + P351 + P338

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Packing Group III

      References

      (1) F.L. Rodkey: Arch. Biochem. Biophys. 94, 38 (1961), (2) T. Hoshi & H. Hayashi: Jpn. J. Physiol. 20, 683 (1970), (3) U. Kragh-Hansen & J.V. Moller: Biochim. Biophys. Acta 295, 438 (1973), (4) Y. Berthois, et al.: PNAS 83, 2496 (1986), (5) P. Yuan & D.R. Walt: J. Fluoresc. 2, 231 (1992), (6) L. Hopp & C.H. Bunker: J. Cell Physiol. 157, 594 (1993), (7) J. Wesierska-Gadek, et al.: Cell Mol. Biol. Lett. 12, 280 (2007), (8) H. Lysdahl, et al.: Stem Cell Rev. 9, 132 (2013)

      InChi

      InChI=1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H

      Quantity

      1 g, 10 g, 50 g, Bulk

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