- ≥96% (GC)
- White to off-white powder
Intermediate formed in the valine catabolism. It is a reactant of the enzymes involved in branched chain amino acid metabolism 3-hydroxyisobutyrate dehydrogenase and 3-hydroxyisobutyryl-CoA hydrolase and it was found to have increased concentrations in MS patient metabolic profiles. This compound may be used to study the distribution, characterization and kinetics of these enzymes. Shown to inhibit key enzymes of the energy metabolism.
(R)-beta-Hydroxyisobutyric acid sodium salt, (R)-3-Hydroxy-2-methylpropionic acid sodium salt, R-HIBA, R-beta-HIBA-Na, Sodium (R)-3-hydroxy-2-methylpropionate
White to off-white powder
|Short Term Storage||
|Long Term Storage||
Protect from light and moisture.
|Use / Stability||
Stable for at least 2 years after receipt when stored at +4°C.
Not dangerous goods
(1) S. Landaas, Clin. Chim. Acta 64, 143 (1975), (2) F. Podebrad, et al., Clin. Chim. Acta 292, 93 (2000), (3) J.W. Hawes, et al., Methods Enzymol. 324, 218 (2000), (4) F.J. Loupatty, et al., Am. J. Hum. Genet. 80, 195 (2007), (5) C.M. Viegas, et al., Int. J. Dev. Neurosci. 26, 293 (2008), (6) R.J. Wanders, et al., J. Inherit. Metab. Dis. 35, 5 (2012)
100 mg, Bulk