Specifications
- Purity
- ≥99% (TLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- methanol
- Melting Point
- 179 °C
Documentation
- Safety Data Sheet (SDS)
- CDX A0147 MSDS.pdf
Available from stock
S-BAIBA
- SKU
- A0147
Category: Metabolites
- Synonyms
- L-3-Amino-isobutyric acid
- 4249-19-8
- CAS-Number
- C4H9NO2
- Molecular Formula
- 103.12
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H319
- Precautionary statements
- P305 + P351 + P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains the R-enantiomer of beta-Aminoisobutyric acid, which is eliminated both by filtration and tubular secretion. The S-enantiomer of beta-Aminoisobutyric acid is predominantly derived from the catabolism of valine, the R-enantiomer is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase (DPD), in what constitutes the first step of the pyrimidine degradation pathway. Transient high levels of beta-Aminoisobutyric acid have been observed under a variety of pathological conditions such as lead poisoning, starvation, in total body irradiation and in a number of malignancies. Recently R-/S-enantiomer mixtures have been shown to be browning inducer of white adipose tissue.
- Smiles
- OC([C@@H](C)CN)=O
- InChi Key
- QCHPKSFMDHPSNR-VKHMYHEASA-N
- References
- (1) S. Landaas & E. Solem: Scand. J. Clin. Lab. Invest. 43, 95 (1983) , (2) F. Podebrad, et al.: Clin. Chim. Acta 292, 93 (2000) , (3) A.B. Van Kuilenburg, et al.: Biochem. J. 379, 119 (2004)
- InChi
- InChI=1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains the R-enantiomer of beta-Aminoisobutyric acid, which is eliminated both by filtration and tubular secretion. The S-enantiomer of beta-Aminoisobutyric acid is predominantly derived from the catabolism of valine, the R-enantiomer is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase (DPD), in what constitutes the first step of the pyrimidine degradation pathway. Transient high levels of beta-Aminoisobutyric acid have been observed under a variety of pathological conditions such as lead poisoning, starvation, in total body irradiation and in a number of malignancies. Recently R-/S-enantiomer mixtures have been shown to be browning inducer of white adipose tissue.
Additional information
| Synonyms | L-3-Amino-isobutyric acid |
|---|---|
| Purity | ≥99% (TLC) |
| Appearance | White to off-white powder |
| CAS-Number | 4249-19-8 |
| Molecular Formula | C4H9NO2 |
| Molecular Weight | 103.12 |
| Identity | 1H-NMR |
| Solvents | methanol |
| Melting Point | 179 °C |
| Smiles | OC([C@@H](C)CN)=O |
| InChi Key | QCHPKSFMDHPSNR-VKHMYHEASA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H319 |
| Precautionary statements | P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) S. Landaas & E. Solem: Scand. J. Clin. Lab. Invest. 43, 95 (1983), (2) F. Podebrad, et al.: Clin. Chim. Acta 292, 93 (2000), (3) A.B. Van Kuilenburg, et al.: Biochem. J. 379, 119 (2004) |
| InChi | InChI=1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1 |
| Quantity | 100 mg, 500 mg, Bulk |
