(S,S)-(-)-1,4-Dimethoxy-2,3-butanediol

SKU: D0434

Category: Building Blocks, Intermediates, Reagents

Synonyms: 1,4-Di-O-methyl-L-threitol; 50622-10-1
CAS-Number: C₆H₁₄O₄
Molecular Formula: 150.17
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥99% (GC)
Identity: 1H-NMR
Appearance: White powder

Properties

Optical Activity: [α]20/D -1.8±0.1°, c = 1.9% in methanol
Boiling Point: 68 °C at 0.2 Torr
Melting Point: 28-30 °C
Solvents: Soluble in chloroform

Shipping: AMBIENT
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.
Handling Advice: Protect from light and moisture.
Long Term Storage: +4°C
Short Term Storage: +4°C

Transportation: Not dangerous goods

Description: Building block for synthesis. For chiral auxiliary modification of LAH. Condensation of ester enolates and chiral imines to ?-lactams. Auxiliary, reactions of its acetal. Determination of the enantiomeric purity of ketones by acetal formation and 13C-NMR.
InChi: InChI=1S/C6H14O4/c1-9-3-5(7)6(8)4-10-2/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1
References: (1) P. Nanasi & A. Liptak: Carbohyd. Res. 29, 201 (1973) , (2) W. Langer & D. Seebach: Helv. Chim. Acta 62, 1710 (1978) , (3) M. Schmidt, et al.: Chem. Ber. 113, 1691 (1980) , (4) A. Alexakis & P. Mangeney: Tetrahed. Asym. 1, 477 (1990) , (5) T. Fujisawa, et al.: Tetrahed. 48, 5629 (1992)
InChi Key: QPXJVYUZWDGUBO-WDSKDSINSA-N
Smiles: COC[C@H](O)[C@@H](O)COC

Building block for synthesis. For chiral auxiliary modification of LAH. Condensation of ester enolates and chiral imines to ?-lactams. Auxiliary, reactions of its acetal. Determination of the enantiomeric purity of ketones by acetal formation and 13C-NMR.

SKU: D0434 Category: Building Blocks, Intermediates, Reagents

Additional information

Additional information

Synonyms	1,4-Di-O-methyl-L-threitol
Purity	≥99% (GC)
Appearance	White powder
CAS-Number	50622-10-1
Molecular Formula	C6H14O4
Molecular Weight	150.17
Identity	1H-NMR
Solvents	Soluble in chloroform
Melting Point	28-30 °C
Boiling Point	68 °C at 0.2 Torr
Optical Activity	[α]20/D -1.8±0.1°, c = 1.9% in methanol
Smiles	COC[C@H](O)[C@@H](O)COC
InChi Key	QPXJVYUZWDGUBO-WDSKDSINSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) P. Nanasi & A. Liptak: Carbohyd. Res. 29, 201 (1973), (2) W. Langer & D. Seebach: Helv. Chim. Acta 62, 1710 (1978), (3) M. Schmidt, et al.: Chem. Ber. 113, 1691 (1980), (4) A. Alexakis & P. Mangeney: Tetrahed. Asym. 1, 477 (1990), (5) T. Fujisawa, et al.: Tetrahed. 48, 5629 (1992)
InChi	InChI=1S/C6H14O4/c1-9-3-5(7)6(8)4-10-2/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1
Quantity	250 mg, 1 g, 5 g, Bulk