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      Thiazol Orange

      SKU
      T0013

      Category: Non Fluorescent Detection & Chromogene Detection

      Synonyms
      1-Methyl-4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]quinolinium p-tosylate
      107091-89-4
      CAS-Number
      C26H24N2O3S2
      Molecular Formula
      476.61
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (HPLC)
      Appearance
      Orange crystalline powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMSO
      Melting Point
      270°C
      Fluorescence
      λex 509 nm, λem 530 nm in 0.1 M phosphate pH 7.0 (bound to ds DNA)

      Documentation

      Safety Data Sheet (SDS)
      CDX T0013 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      +4°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Hazard statements
      H315, H319, H335
      Precautionary statements
      P261, P305 + P351 + P338
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      Thiazol Orange is a nucleic acid stain that has found applications in many different areas. Among others it is used for reticulocyte analysis and Plasmodium species analysis as well as labeling cancer cells. Thiazole orange-labeled DNA has been used for live cell RNA imaging. Thiazole Orange has also been used for a variety of assays, PCR and flow cytometry.
      Smiles
      CC1=CC=C(C=C1)S([O-])(=O)=O.CN1C(SC2=C1C=CC=C2)=C[N+]1=CC=C(C)C2=CC=CC=C12
      InChi Key
      NYWVUHLUVDLMPB-OKOHOLKASA-M
      References
      (1) T. Kubota et al.: Bull. Chem. Soc. Jap. 82(1), 110 (2009) , (2) X. Fei et al.: Bioorg. & Med. Chem.17(2), 585 (2009) , (3) S. Ikeda et al.: Biocon. Chem. 19(8), 1719 (2008)
      InChi
      InChI=1S/C19H17N2S.C7H8O3S/c1-14-11-12-21(16-8-4-3-7-15(14)16)13-19-20(2)17-9-5-6-10-18(17)22-19

      Thiazol Orange is a nucleic acid stain that has found applications in many different areas. Among others it is used for reticulocyte analysis and Plasmodium species analysis as well as labeling cancer cells. Thiazole orange-labeled DNA has been used for live cell RNA imaging. Thiazole Orange has also been used for a variety of assays, PCR and flow cytometry.

      SKU: T0013 Category: Non Fluorescent Detection & Chromogene Detection
      • Additional information

      Additional information

      Synonyms

      1-Methyl-4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]quinolinium p-tosylate

      Purity

      ≥98% (HPLC)

      Appearance

      Orange crystalline powder

      CAS-Number

      107091-89-4

      Molecular Formula

      C26H24N2O3S2

      Molecular Weight

      476.61

      Identity

      1H-NMR

      Solvents

      DMSO

      Melting Point

      270°C

      Fluorescence

      λex 509 nm, λem 530 nm in 0.1 M phosphate pH 7.0 (bound to ds DNA)

      Smiles

      CC1=CC=C(C=C1)S([O-])(=O)=O.CN1C(SC2=C1C=CC=C2)=C[N+]1=CC=C(C)C2=CC=CC=C12

      InChi Key

      NYWVUHLUVDLMPB-OKOHOLKASA-M

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Hazard statements

      H315, H319, H335

      Precautionary statements

      P261, P305 + P351 + P338

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) T. Kubota et al.: Bull. Chem. Soc. Jap. 82(1), 110 (2009), (2) X. Fei et al.: Bioorg. & Med. Chem.17(2), 585 (2009), (3) S. Ikeda et al.: Biocon. Chem. 19(8), 1719 (2008)

      InChi

      InChI=1S/C19H17N2S.C7H8O3S/c1-14-11-12-21(16-8-4-3-7-15(14)16)13-19-20(2)17-9-5-6-10-18(17)22-19

      Quantity

      250 mg, 5 g, Bulk

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