Thiazol Orange
- SKU
- T0013
Category: Non Fluorescent Detection & Chromogene Detection
- Synonyms
- 1-Methyl-4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]quinolinium p-tosylate
- 107091-89-4
- CAS-Number
- C26H24N2O3S2
- Molecular Formula
- 476.61
- Molecular Weight
Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- Orange crystalline powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO
- Melting Point
- 270°C
- Fluorescence
- λex 509 nm, λem 530 nm in 0.1 M phosphate pH 7.0 (bound to ds DNA)
Documentation
- Safety Data Sheet (SDS)
- CDX T0013 MSDS.pdf
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H315, H319, H335
- Precautionary statements
- P261, P305 + P351 + P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- For Research Use Only
- Not Intended for Diagnostic or Therapeutic Use.
- Description
- Thiazol Orange is a nucleic acid stain that has found applications in many different areas. Among others it is used for reticulocyte analysis and Plasmodium species analysis as well as labeling cancer cells. Thiazole orange-labeled DNA has been used for live cell RNA imaging. Thiazole Orange has also been used for a variety of assays, PCR and flow cytometry.
- Smiles
- CC1=CC=C(C=C1)S([O-])(=O)=O.CN1C(SC2=C1C=CC=C2)=C[N+]1=CC=C(C)C2=CC=CC=C12
- InChi Key
- NYWVUHLUVDLMPB-OKOHOLKASA-M
- References
- (1) T. Kubota et al.: Bull. Chem. Soc. Jap. 82(1), 110 (2009) , (2) X. Fei et al.: Bioorg. & Med. Chem.17(2), 585 (2009) , (3) S. Ikeda et al.: Biocon. Chem. 19(8), 1719 (2008)
- InChi
- InChI=1S/C19H17N2S.C7H8O3S/c1-14-11-12-21(16-8-4-3-7-15(14)16)13-19-20(2)17-9-5-6-10-18(17)22-19
Thiazol Orange is a nucleic acid stain that has found applications in many different areas. Among others it is used for reticulocyte analysis and Plasmodium species analysis as well as labeling cancer cells. Thiazole orange-labeled DNA has been used for live cell RNA imaging. Thiazole Orange has also been used for a variety of assays, PCR and flow cytometry.