Specifications
- Purity
- ≥97% (NMR)
- Appearance
- Off-white to yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (2 mg/ml), DMF (20 mg/ml)
- UV / Vis
- λmax: 225 nm
Available from stock
WSP1
- SKU
- W0001
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- 3'-Methoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl 2-(pyridin-2-yldisulfanyl)benzoate , Washington State Probe-1
- 1352750-34-5
- CAS-Number
- C33H21NO6S2
- Molecular Formula
- 591.65
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305 + P351 + P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Packing Group III
- Description
- Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.
- Smiles
- O=C(C1=C2C=CC=C1)OC32C4=CC=C(OC(C5=CC=CC=C5SSC6=CC=CC=N6)=O)C=C4OC7=CC(OC)=CC=C73
- InChi Key
- VHKQAUGSGQUCDU-UHFFFAOYSA-N
- References
- (1) C. Liu, et al.: Angew. Chem. Int. Ed. Engl. 50, 10327 (2011)
- InChi
- InChI=1S/C33H21NO6S2/c1-37-20-13-15-25-27(18-20)39-28-19-21(14-16-26(28)33(25)24-10-4-2-8-22(24)32(36)40-33)38-31(35)23-9-3-5-11-29(23)41-42-30-12-6-7-17-34-30/h2-19H,1H3
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.
Additional information
| Synonyms | 3'-Methoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl 2-(pyridin-2-yldisulfanyl)benzoate, Washington State Probe-1 |
|---|---|
| Purity | ≥97% (NMR) |
| Appearance | Off-white to yellow powder |
| CAS-Number | 1352750-34-5 |
| Molecular Formula | C33H21NO6S2 |
| Molecular Weight | 591.65 |
| Identity | 1H-NMR |
| Solvents | DMSO (2 mg/ml), DMF (20 mg/ml) |
| UV / Vis | λmax: 225 nm |
| Smiles | O=C(C1=C2C=CC=C1)OC32C4=CC=C(OC(C5=CC=CC=C5SSC6=CC=CC=N6)=O)C=C4OC7=CC(OC)=CC=C73 |
| InChi Key | VHKQAUGSGQUCDU-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Packing Group III |
| References | (1) C. Liu, et al.: Angew. Chem. Int. Ed. Engl. 50, 10327 (2011) |
| InChi | InChI=1S/C33H21NO6S2/c1-37-20-13-15-25-27(18-20)39-28-19-21(14-16-26(28)33(25)24-10-4-2-8-22(24)32(36)40-33)38-31(35)23-9-3-5-11-29(23)41-42-30-12-6-7-17-34-30/h2-19H,1H3 |
| Quantity | 5 mg, 25 mg, Bulk |
