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    5-ROX

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      5-ROX

      SKU
      C0004

      Categories: Fluorescent Detection, Fluorescent Detection

      Synonyms
      5-Carboxy-X-rhodamine , 5-CXR
      216699-35-3
      CAS-Number
      C33H30N2O5
      Molecular Formula
      534.6
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥95% (HPLC)
      Appearance
      Green powder
      Identity
      1H-NMR

      Properties

      Solvents
      methanol, DMSO, DMF
      Fluorescence
      λex 575 nm, λem 600 nm

      Documentation

      Safety Data Sheet (SDS)
      CDX C0004 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      +4°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Hazard statements
      H315, H319, H335
      Precautionary statements
      P261, P305 + P351 + P338
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties of the underlying conjugates. Used for oligonucleotide labeling and automated DNA sequencing applications.
      Smiles
      OC(=O)C1=CC=C(C(=C1)C([O-])=O)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34
      InChi Key
      UNGMOMJDNDFGJG-UHFFFAOYSA-N
      References
      (1) P.J. Finn et al.: Nucleic Acids Res. 30, 2877 (2002) , (2) J.M. Bartlett et al.: Mol Biotechnol 13, 185 (1999) , (3) S.C. Hung et al.: Anal Biochem 255, 32 (1998)
      InChi
      InChI=1S/C33H30N2O5/c36-32(37)20-9-10-21(24(17-20)33(38)39)27-25-15-18-5-1-11-34-13-3-7-22(28(18)34)30(25)40-31-23-8-4-14-35-12-2-6-19(29(23)35)16-26(27)31/h9-10,15-17H,1-8,11-14H2,(H-,36,37,38,39)

      5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties of the underlying conjugates. Used for oligonucleotide labeling and automated DNA sequencing applications.

      SKU: C0004 Categories: Fluorescent Detection, Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      5-Carboxy-X-rhodamine, 5-CXR

      Purity

      ≥95% (HPLC)

      Appearance

      Green powder

      CAS-Number

      216699-35-3

      Molecular Formula

      C33H30N2O5

      Molecular Weight

      534.6

      Identity

      1H-NMR

      Solvents

      methanol, DMSO, DMF

      Fluorescence

      λex 575 nm, λem 600 nm

      Smiles

      OC(=O)C1=CC=C(C(=C1)C([O-])=O)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34

      InChi Key

      UNGMOMJDNDFGJG-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Hazard statements

      H315, H319, H335

      Precautionary statements

      P261, P305 + P351 + P338

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) P.J. Finn et al.: Nucleic Acids Res. 30, 2877 (2002), (2) J.M. Bartlett et al.: Mol Biotechnol 13, 185 (1999), (3) S.C. Hung et al.: Anal Biochem 255, 32 (1998)

      InChi

      InChI=1S/C33H30N2O5/c36-32(37)20-9-10-21(24(17-20)33(38)39)27-25-15-18-5-1-11-34-13-3-7-22(28(18)34)30(25)40-31-23-8-4-14-35-12-2-6-19(29(23)35)16-26(27)31/h9-10,15-17H,1-8,11-14H2,(H-,36,37,38,39)

      Quantity

      20 mg, 200 mg, Bulk

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