Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in chloroform or methanol.
Category: API's & Intermediates
Aripiprazole is an atypical antipsychotic. Aripiprazole is a partial agonist at dopamine D2 receptors, partial agonist at 5-HT1A receptors and an antagonist at 5-HT2A, receptors. 7-(4-Bromobutoxy)-3,4-dihydroquinolin-2(1H)-one is an intermediate used for the synthesis of Aripirazole. This compound can be used as a reference compound for this impurity and potential degradation product.
Synonyms | Aripiprazole Impurity |
---|---|
Purity | ≥98% (HPLC) |
Appearance | White to off-white powder |
CAS-Number | 129722-34-5 |
Molecular Formula | C13H16BrNO2 |
Molecular Weight | 298.18 |
Identity | 1H-NMR |
Solvents | Soluble in chloroform or methanol. |
Smiles | O=C(CC1)NC2=C1C=CC(OCCCCBr)=C2 |
InChi Key | URHLNHVYMNBPEO-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | RT |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
Hazard statements | H302, H315, H319, H332, H335 |
Precautionary statements | P261, P280, P305, P338, P351 |
GHS Symbol | GHS07 |
Signal word | Warning |
Transportation | Not dangerous goods |
References | (1) Y. Oshiro, et al., J. Med. Chem. 41,658 (1998), (2) H.-X. Ge, et al., Arzneim.-Forsch./Drug Res. 56, 673 (2006), (3) T. Poorna Chander, et al., Synthet. Commun. 37, 4337 (2007), (4) K.S.V. Srinivas, et al., Chromatographia 68, 635 (2008) |
Quantity | 1 g, Bulk |