Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (20 mg/ml), DMF (20 mg/ml), ethanol (2 mg/ml)
- Melting Point
- 230 °C
- Refractive Index
- -24°, c = 0.1 in DMSO
Category: Phytochemicals
Daidzin is a naturally occuring isoflavone. It is the major active component of the traditional Chinese medicine (TCM) derived from radix puerariae (Kudzu) that is commonly used to treat alcohol abuse. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (ALDH-2) (IC50=80nM) and is an effective anti-dipsotropic isoflavone.
Synonyms | Daidzein-7-O-β-D-glucopyranoside, Daidzoside, NPI 031D, BRN 0059741 |
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Purity | ≥98% (HPLC) |
Appearance | White powder |
CAS-Number | 552-66-9 |
Molecular Formula | C21H20O9 |
Molecular Weight | 416.38 |
Identity | 1H-NMR |
Solvents | DMSO (20 mg/ml), DMF (20 mg/ml), ethanol (2 mg/ml) |
Melting Point | 230 °C |
Refractive Index | -24°, c = 0.1 in DMSO |
Smiles | O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC=C31 |
InChi Key | KYQZWONCHDNPDP-QNDFHXLGSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Transportation | Not dangerous goods |
References | (1) W.M. Keung & B.L. Vallee, PNAS 90, 1247 (1993), (2) C.I. Xie, et al., Alcohol Clin. Exp. Res. 18, 1443 (1994), (3) W.M. Keung & B.L. Vallee, PNAS 95, 2198 (1998), (4) K. Kato, et al., Jpn. J. Cancer Res. 91, 786 (2000), (5) X.H. Li, et al., Acta Pharmacol. Sin. 26, 1081 (2005), (6) E.D. Lowe, et al., J. Med. Chem. 51, 4482 (2008), (7) Y. Zang, et al., Biosci. Biotechnol. Biochem. 79, 117 (2015), (8) G. Wei, et al., J. Cell Biochem. 120, 5304 (2019) |
InChi | InChI=1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1 |
Quantity | 5 mg, 25 mg, Bulk |