Available from stock

Daidzin

SKU: D0926

Category: Phytochemicals

Synonyms: Daidzein-7-O-β-D-glucopyranoside , Daidzoside , NPI 031D , BRN 0059741; 552-66-9
CAS-Number: C₂₁H₂₀O₉
Molecular Formula: 416.38
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: White powder
Identity: 1H-NMR

Properties

Solvents: DMSO (20 mg/ml), DMF (20 mg/ml), ethanol (2 mg/ml)
Melting Point: 230 °C
Refractive Index: -24°, c = 0.1 in DMSO

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Transportation: Not dangerous goods

Description: Daidzin is a naturally occuring isoflavone. It is the major active component of the traditional Chinese medicine (TCM) derived from radix puerariae (Kudzu) that is commonly used to treat alcohol abuse. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (ALDH-2) (IC50=80nM) and is an effective anti-dipsotropic isoflavone.
Smiles: O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC=C31
InChi Key: KYQZWONCHDNPDP-QNDFHXLGSA-N
References: (1) W.M. Keung & B.L. Vallee, PNAS 90, 1247 (1993) , (2) C.I. Xie, et al., Alcohol Clin. Exp. Res. 18, 1443 (1994) , (3) W.M. Keung & B.L. Vallee, PNAS 95, 2198 (1998) , (4) K. Kato, et al., Jpn. J. Cancer Res. 91, 786 (2000) , (5) X.H. Li, et al., Acta Pharmacol. Sin. 26, 1081 (2005) , (6) E.D. Lowe, et al., J. Med. Chem. 51, 4482 (2008) , (7) Y. Zang, et al., Biosci. Biotechnol. Biochem. 79, 117 (2015) , (8) G. Wei, et al., J. Cell Biochem. 120, 5304 (2019)
InChi: InChI=1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1

Daidzin is a naturally occuring isoflavone. It is the major active component of the traditional Chinese medicine (TCM) derived from radix puerariae (Kudzu) that is commonly used to treat alcohol abuse. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (ALDH-2) (IC50=80nM) and is an effective anti-dipsotropic isoflavone.

SKU: D0926 Category: Phytochemicals

Additional information

Additional information

Synonyms	Daidzein-7-O-β-D-glucopyranoside, Daidzoside, NPI 031D, BRN 0059741
Purity	≥98% (HPLC)
Appearance	White powder
CAS-Number	552-66-9
Molecular Formula	C21H20O9
Molecular Weight	416.38
Identity	1H-NMR
Solvents	DMSO (20 mg/ml), DMF (20 mg/ml), ethanol (2 mg/ml)
Melting Point	230 °C
Refractive Index	-24°, c = 0.1 in DMSO
Smiles	O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC=C31
InChi Key	KYQZWONCHDNPDP-QNDFHXLGSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) W.M. Keung & B.L. Vallee, PNAS 90, 1247 (1993), (2) C.I. Xie, et al., Alcohol Clin. Exp. Res. 18, 1443 (1994), (3) W.M. Keung & B.L. Vallee, PNAS 95, 2198 (1998), (4) K. Kato, et al., Jpn. J. Cancer Res. 91, 786 (2000), (5) X.H. Li, et al., Acta Pharmacol. Sin. 26, 1081 (2005), (6) E.D. Lowe, et al., J. Med. Chem. 51, 4482 (2008), (7) Y. Zang, et al., Biosci. Biotechnol. Biochem. 79, 117 (2015), (8) G. Wei, et al., J. Cell Biochem. 120, 5304 (2019)
InChi	InChI=1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1
Quantity	5 mg, 25 mg, Bulk