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    Guanosine

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      Guanosine

      SKU
      G0035

      Category: Phytochemicals

      Synonyms
      9-β-D-Ribofuranosyl-guanine , Guanine-9-β-D-ribofuranoside , 2-Amino-9-β-D-ribofuranosyl-9H-purine-6-(1H)-one
      118-00-3
      CAS-Number
      C10H13N5O5
      Molecular Formula
      283.24
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (HPLC)
      Identity
      1H-NMR
      Appearance
      White to light yellow powder

      Properties

      Melting Point
      250°C (dec)
      Solvents
      formic acid:water (1:1) (~50mg/ml)

      Downloads

      Safety Data Sheet
      CDX G0035 MSDS.pdf
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Long Term Storage
      +4°C
      Short Term Storage
      +4°C
      Shipping
      AMBIENT
      Transportation
      Packing Group III
      RIDADR
      UN 2811 6.1
      Signal word
      Danger
      GHS Symbol
      GHS06
      Precautionary statements
      P301+P310
      Hazard statements
      H301
      Description
      "Purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a ?-N9-glycosidic bond. Can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP) and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). Guanosine has important functions in cell metabolism and a protective role in response to degenerative diseases or injury with neurotrophic and neuroprotective effects. Required for an RNA splicing reaction in mRNA, when a ""self-splicing"" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein."
      InChi
      InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
      References
      M. Rathbone, et al., Nucleosides Nucleotides Nucleic Acids 27, 666 (2008) , D. Lanznaster, et al., Aging Dis. 7, 657 (2016)
      InChi Key
      NYHBQMYGNKIUIF-UUOKFMHZSA-N
      Smiles
      O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO

      “Purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a ?-N9-glycosidic bond. Can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP) and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). Guanosine has important functions in cell metabolism and a protective role in response to degenerative diseases or injury with neurotrophic and neuroprotective effects. Required for an RNA splicing reaction in mRNA, when a “”self-splicing”” intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein.”

      SKU: G0035 Category: Phytochemicals
      • Additional information

      Additional information

      Synonyms

      9-β-D-Ribofuranosyl-guanine, Guanine-9-β-D-ribofuranoside, 2-Amino-9-β-D-ribofuranosyl-9H-purine-6-(1H)-one

      Purity

      ≥98% (HPLC)

      Appearance

      White to light yellow powder

      CAS-Number

      118-00-3

      Molecular Formula

      C10H13N5O5

      Molecular Weight

      283.24

      Identity

      1H-NMR

      Solvents

      formic acid:water (1:1) (~50mg/ml)

      Melting Point

      250°C (dec)

      Smiles

      O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO

      InChi Key

      NYHBQMYGNKIUIF-UUOKFMHZSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Hazard statements

      H301

      Precautionary statements

      P301+P310

      GHS Symbol

      GHS06

      Signal word

      Danger

      RIDADR

      UN 2811 6.1

      Transportation

      Packing Group III

      References

      M. Rathbone, et al., Nucleosides Nucleotides Nucleic Acids 27, 666 (2008), D. Lanznaster, et al., Aging Dis. 7, 657 (2016)

      InChi

      InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

      Quantity

      5 g, 50 g, 100 g, Bulk

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