Specifications
- Purity
- ≥98% (HPLC)
- Identity
- 1H-NMR
- Appearance
- White to light yellow powder
Properties
- Melting Point
- 250°C (dec)
- Solvents
- formic acid:water (1:1) (~50mg/ml)
Downloads
- Safety Data Sheet
- CDX G0035 MSDS.pdf
Available from stock
Guanosine
- SKU
- G0035
Category: Phytochemicals
- Synonyms
- 9-β-D-Ribofuranosyl-guanine , Guanine-9-β-D-ribofuranoside , 2-Amino-9-β-D-ribofuranosyl-9H-purine-6-(1H)-one
- 118-00-3
- CAS-Number
- C10H13N5O5
- Molecular Formula
- 283.24
- Molecular Weight
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Long Term Storage
- +4°C
- Short Term Storage
- +4°C
- Shipping
- AMBIENT
- Transportation
- Packing Group III
- RIDADR
- UN 2811 6.1
- Signal word
- Danger
- GHS Symbol
- GHS06
- Precautionary statements
- P301+P310
- Hazard statements
- H301
- Description
- "Purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a ?-N9-glycosidic bond. Can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP) and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). Guanosine has important functions in cell metabolism and a protective role in response to degenerative diseases or injury with neurotrophic and neuroprotective effects. Required for an RNA splicing reaction in mRNA, when a ""self-splicing"" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein."
- InChi
- InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
- References
- M. Rathbone, et al., Nucleosides Nucleotides Nucleic Acids 27, 666 (2008) , D. Lanznaster, et al., Aging Dis. 7, 657 (2016)
- InChi Key
- NYHBQMYGNKIUIF-UUOKFMHZSA-N
- Smiles
- O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO
“Purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a ?-N9-glycosidic bond. Can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP) and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). Guanosine has important functions in cell metabolism and a protective role in response to degenerative diseases or injury with neurotrophic and neuroprotective effects. Required for an RNA splicing reaction in mRNA, when a “”self-splicing”” intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein.”
Additional information
| Synonyms | 9-β-D-Ribofuranosyl-guanine, Guanine-9-β-D-ribofuranoside, 2-Amino-9-β-D-ribofuranosyl-9H-purine-6-(1H)-one |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to light yellow powder |
| CAS-Number | 118-00-3 |
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.24 |
| Identity | 1H-NMR |
| Solvents | formic acid:water (1:1) (~50mg/ml) |
| Melting Point | 250°C (dec) |
| Smiles | O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO |
| InChi Key | NYHBQMYGNKIUIF-UUOKFMHZSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H301 |
| Precautionary statements | P301+P310 |
| GHS Symbol | GHS06 |
| Signal word | Danger |
| RIDADR | UN 2811 6.1 |
| Transportation | Packing Group III |
| References | M. Rathbone, et al., Nucleosides Nucleotides Nucleic Acids 27, 666 (2008), D. Lanznaster, et al., Aging Dis. 7, 657 (2016) |
| InChi | InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1 |
| Quantity | 5 g, 50 g, 100 g, Bulk |
