Specifications
- Purity
- ≥98% (TLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
- Water content (K.F.)
- ≤12%
Properties
- Solvents
- Soluble in water.
- Melting Point
- 215 °C (dec.) (lit.)
Category: Amino Acids, Peptides, Proteins
L-Lysine is an essential α-amino acid, which is encoded by the codons AAA and AAG. It is a key building block in protein synthesis in which it acts as a base. Lysine residues are useful in many cellular processes, due to their ability to accept a wide variety of post-translational modifications. These modifications include acetylation, methylation, ubiquitination, sumoylation, neddylation, biotinylation, pupylation and carboxylation. L-lysine is an essential amino acid that cannot be synthesized by humans and mammals through transamination. Lysine plays a pivotal role in different processes inside the human body, such as proteinogenesis, catalysis, fatty acid metabolism, histone modification, polypeptide crosslinking, calcium homeostasis, and acts as a nucleophile in enzymatic reactions. Because of its pivotal role in promoting growth and development, enhancing immunity, and preventing cardiovascular and cerebrovascular diseases, L-lysine is used in food health care, feed additives and pharmaceutical preparations.
Synonyms | H-Lys-OH, (S)-Lysine, (S)-2,6-Diaminocaproic acid |
---|---|
Purity | ≥98% (TLC) |
Appearance | White to off-white powder |
CAS-Number | 56-87-1 |
Molecular Formula | C6H14N2O2 |
Molecular Weight | 146.19 |
Identity | 1H-NMR |
Solvents | Soluble in water. |
Melting Point | 215 °C (dec.) (lit.) |
Smiles | NCCCC[C@H](N)C(O)=O |
InChi Key | KDXKERNSBIXSRK-YFKPBYRVSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | RT |
Handling Advice | Very hygroscopic. Store under inert gas. |
Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
Transportation | Not dangerous goods |
References | (1) M. Smriga & K. Torii, PNAS 100, 15370 (2003), (2) L. Tosha, al.: Biochem. J. 435, 509 (2011), (3) F.-M. Boisvert, et al., Mol. Cell Proteomics 11, M111.011429 (2012), (4) F.K.D.C Felix, et al., Crit. Rev. Biotechnol. 39, 1031 (2019), (5) K. Hayamizu, et al., J. Nutr. 150, 2561S (2020), (6) D. Zhang, et al., J. Agric. Food Chem. 69, 3189 (2021), (7) Q. Li, et al., Molecules 27, 35209157 (2022), (8) S. Muduli, et al., Biochim. Biophys. acta 1867, 130320 (2023) |
Quantity | 1 g, Bulk |
cdx-Water content (K.F.) | ≤12% |
cdx-Solubility (method) | 100 mg/ml water |
cdx-Colorless to very faint green-yellow clear | Solubility (color) |