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    Myricetin

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      Myricetin

      SKU
      M0504

      Category: Phytochemicals

      Synonyms
      3,3',4',5,5',7-Hexahydroxyflavone , Cannabiscetin , Myricetol , NSC 407290
      529-44-2
      CAS-Number
      C15H10O8
      Molecular Formula
      318.24
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (HPLC)
      Appearance
      Yellow powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMSO (10 mg/ml), DMF (10 mg/ml), ethanol (2 mg/ml)

      Documentation

      Safety Data Sheet (SDS)
      CDX M0504 SDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Transportation
      Not dangerous goods
      Description
      Myricetin is a naturally occurring flavonol with powerful antioxidant property. It also exhibits a wide range of additional effects that include, anticancer, antidiabetic, neuroprotective and anti-inflammatory activities. It is also used as a preserving agent to extend the shelf life of foods containing oils and fats, based on it's ability to protect lipids against oxidation. Myricetin has been shown to suppress cancer cell invasion and metastasis, to induce cell cycle arrest and apoptosis of cancer cells and to inhibit their proliferation. Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination.
      Smiles
      OC1=C2C(OC(C3=CC(O)=C(O)C(O)=C3)=C(O)C2=O)=CC(O)=C1
      InChi Key
      IKMDFBPHZNJCSN-UHFFFAOYSA-N
      References
      (1) K.C. Ong & H.E. Khoo, Gen. Pharmacol. 29, 121 (1997) (Review) , (2) K.P. Devi, et al., Life Sci. 142, 19 (2015) (Review) , (3) D.K. Semwal, et al., Nutrients 8, 90 (2016) (Review) , (4) M. Jiang, et al., Biomed. Pharmacother. 120, 109506 (2019) (Review) , (5) H. Chen, et al., Toxicol. Appl. Pharmacol. 365, 19 (2019)
      InChi
      InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H

      Myricetin is a naturally occurring flavonol with powerful antioxidant property. It also exhibits a wide range of additional effects that include, anticancer, antidiabetic, neuroprotective and anti-inflammatory activities. It is also used as a preserving agent to extend the shelf life of foods containing oils and fats, based on it’s ability to protect lipids against oxidation. Myricetin has been shown to suppress cancer cell invasion and metastasis, to induce cell cycle arrest and apoptosis of cancer cells and to inhibit their proliferation. Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination.

      SKU: M0504 Category: Phytochemicals
      • Additional information

      Additional information

      Synonyms

      3,3',4',5,5',7-Hexahydroxyflavone, Cannabiscetin, Myricetol, NSC 407290

      Purity

      ≥98% (HPLC)

      Appearance

      Yellow powder

      CAS-Number

      529-44-2

      Molecular Formula

      C15H10O8

      Molecular Weight

      318.24

      Identity

      1H-NMR

      Solvents

      DMSO (10 mg/ml), DMF (10 mg/ml), ethanol (2 mg/ml)

      Smiles

      OC1=C2C(OC(C3=CC(O)=C(O)C(O)=C3)=C(O)C2=O)=CC(O)=C1

      InChi Key

      IKMDFBPHZNJCSN-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Transportation

      Not dangerous goods

      References

      (1) K.C. Ong & H.E. Khoo, Gen. Pharmacol. 29, 121 (1997) (Review), (2) K.P. Devi, et al., Life Sci. 142, 19 (2015) (Review), (3) D.K. Semwal, et al., Nutrients 8, 90 (2016) (Review), (4) M. Jiang, et al., Biomed. Pharmacother. 120, 109506 (2019) (Review), (5) H. Chen, et al., Toxicol. Appl. Pharmacol. 365, 19 (2019)

      InChi

      InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H

      Quantity

      25 mg, 100 mg, Bulk

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