Specifications
- Purity
- ≥98% (HPLC)
- Identity
- 1H-NMR
- Appearance
- Yellow powder
Properties
- Solvents
- DMSO (10 mg/ml), DMF (10 mg/ml), ethanol (2 mg/ml)
Available from stock
Myricetin
- SKU
- M0504
Category: Phytochemicals
- Synonyms
- 3,3',4',5,5',7-Hexahydroxyflavone , Cannabiscetin , Myricetol , NSC 407290
- 529-44-2
- CAS-Number
- C15H10O8
- Molecular Formula
- 318.24
- Molecular Weight
- Short Term Storage
- +4°C
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Handling Advice
- Protect from light and moisture.
- Long Term Storage
- -20°C
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Description
- Myricetin is a naturally occurring flavonol with powerful antioxidant property. It also exhibits a wide range of additional effects that include, anticancer, antidiabetic, neuroprotective and anti-inflammatory activities. It is also used as a preserving agent to extend the shelf life of foods containing oils and fats, based on it's ability to protect lipids against oxidation. Myricetin has been shown to suppress cancer cell invasion and metastasis, to induce cell cycle arrest and apoptosis of cancer cells and to inhibit their proliferation. Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination.
- InChi
- InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
- References
- (1) K.C. Ong & H.E. Khoo, Gen. Pharmacol. 29, 121 (1997) (Review) , (2) K.P. Devi, et al., Life Sci. 142, 19 (2015) (Review) , (3) D.K. Semwal, et al., Nutrients 8, 90 (2016) (Review) , (4) M. Jiang, et al., Biomed. Pharmacother. 120, 109506 (2019) (Review) , (5) H. Chen, et al., Toxicol. Appl. Pharmacol. 365, 19 (2019)
- InChi Key
- IKMDFBPHZNJCSN-UHFFFAOYSA-N
- Smiles
- OC1=C2C(OC(C3=CC(O)=C(O)C(O)=C3)=C(O)C2=O)=CC(O)=C1
Myricetin is a naturally occurring flavonol with powerful antioxidant property. It also exhibits a wide range of additional effects that include, anticancer, antidiabetic, neuroprotective and anti-inflammatory activities. It is also used as a preserving agent to extend the shelf life of foods containing oils and fats, based on it’s ability to protect lipids against oxidation. Myricetin has been shown to suppress cancer cell invasion and metastasis, to induce cell cycle arrest and apoptosis of cancer cells and to inhibit their proliferation. Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination.
Additional information
| Synonyms | 3,3',4',5,5',7-Hexahydroxyflavone, Cannabiscetin, Myricetol, NSC 407290 |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | Yellow powder |
| CAS-Number | 529-44-2 |
| Molecular Formula | C15H10O8 |
| Molecular Weight | 318.24 |
| Identity | 1H-NMR |
| Solvents | DMSO (10 mg/ml), DMF (10 mg/ml), ethanol (2 mg/ml) |
| Smiles | OC1=C2C(OC(C3=CC(O)=C(O)C(O)=C3)=C(O)C2=O)=CC(O)=C1 |
| InChi Key | IKMDFBPHZNJCSN-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Transportation | Not dangerous goods |
| References | (1) K.C. Ong & H.E. Khoo, Gen. Pharmacol. 29, 121 (1997) (Review), (2) K.P. Devi, et al., Life Sci. 142, 19 (2015) (Review), (3) D.K. Semwal, et al., Nutrients 8, 90 (2016) (Review), (4) M. Jiang, et al., Biomed. Pharmacother. 120, 109506 (2019) (Review), (5) H. Chen, et al., Toxicol. Appl. Pharmacol. 365, 19 (2019) |
| InChi | InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H |
| Quantity | 25 mg, 100 mg, Bulk |
