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    Naphthol AS

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      Naphthol AS

      SKU
      N0529

      Category: Non Fluorescent Detection & Chromogene Detection

      Synonyms
      3-Hydroxy-2-naphthanilide
      92-77-3
      CAS-Number
      C17H13NO2
      Molecular Formula
      263.30
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥99% (HPLC)
      Appearance
      White to off-white powder
      Identity
      1H-NMR

      Properties

      Solvents
      Soluble in EtOAc. Slightly soluble in methanol.
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H315-H317-H319-H411
      Precautionary statements
      P261-P280-P273-P305+P351+P338
      GHS Symbol
      GHS07+GHS09
      Signal word
      Danger
      RIDADR
      UN3077
      Transportation
      Packing Group III
      Description
      Naphthol AS (3-Hydroxy-2-naphthanilide) is a fluorescent dye commonly used as a building block or intermediate to produce fluorigenic substrates, bioactive chemicals or as a coupling reagent to produce azo dyes. After cleavage of the fluorigenic substrates by esterases the free Naphthol AS can couple with diazonium salts to form different types of fluorescent azo dyes. 3-Hydroxy-2-naphthanilide (3HNA) is also a naturally occurring chemical that can be found in human urine. It is used as a marker for early pregnancy.
      Smiles
      O=C(NC1=CC=CC=C1)C2=CC3=CC=CC=C3C=C2O
      InChi Key
      JFGQHAHJWJBOPD-UHFFFAOYSA-N
      References
      (1) B.L. Kaul, et al., Chimia 19, 213 (1965) , (2) M. Hueckel, Text. Chem. Color. 1, 510 (1969) , (3) A. Vaughan, et al., Anal. Chem. 43, 721 (1971) , (4) D.M. Hall, et al., Text. Res. J. 50, 692 (1980) , (5) Y. Sumi, et al., Histochem. 73, 481 (1982) , (6) K.-Y. Lee, et al., Dyes Pigm. 23, 243 (1993) , (7) S. Fujita, et al., Anal. Chem. 66, 1347 (1994) , (8) C. Daescu & D. Hadaruga, Dyes Pigm. 40, 235 (1999) , (9) V.A. Vaillancourt, et al., Bioorg. Med. Chem. Lett. 10, 2079 (2000)

      Naphthol AS (3-Hydroxy-2-naphthanilide) is a fluorescent dye commonly used as a building block or intermediate to produce fluorigenic substrates, bioactive chemicals or as a coupling reagent to produce azo dyes. After cleavage of the fluorigenic substrates by esterases the free Naphthol AS can couple with diazonium salts to form different types of fluorescent azo dyes. 3-Hydroxy-2-naphthanilide (3HNA) is also a naturally occurring chemical that can be found in human urine. It is used as a marker for early pregnancy.

      SKU: N0529 Category: Non Fluorescent Detection & Chromogene Detection
      • Additional information

      Additional information

      Synonyms

      3-Hydroxy-2-naphthanilide

      Purity

      ≥99% (HPLC)

      Appearance

      White to off-white powder

      CAS-Number

      92-77-3

      Molecular Formula

      C17H13NO2

      Molecular Weight

      263.30

      Identity

      1H-NMR

      Solvents

      Soluble in EtOAc. Slightly soluble in methanol.

      Smiles

      O=C(NC1=CC=CC=C1)C2=CC3=CC=CC=C3C=C2O

      InChi Key

      JFGQHAHJWJBOPD-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H315-H317-H319-H411

      Precautionary statements

      P261-P280-P273-P305+P351+P338

      GHS Symbol

      GHS07+GHS09

      Signal word

      Danger

      RIDADR

      UN3077

      Transportation

      Packing Group III

      References

      (1) B.L. Kaul, et al., Chimia 19, 213 (1965), (2) M. Hueckel, Text. Chem. Color. 1, 510 (1969), (3) A. Vaughan, et al., Anal. Chem. 43, 721 (1971), (4) D.M. Hall, et al., Text. Res. J. 50, 692 (1980), (5) Y. Sumi, et al., Histochem. 73, 481 (1982), (6) K.-Y. Lee, et al., Dyes Pigm. 23, 243 (1993), (7) S. Fujita, et al., Anal. Chem. 66, 1347 (1994), (8) C. Daescu & D. Hadaruga, Dyes Pigm. 40, 235 (1999), (9) V.A. Vaillancourt, et al., Bioorg. Med. Chem. Lett. 10, 2079 (2000)

      Quantity

      25 g, Bulk

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