N-(2-Aminoethyl)biotinamide hydrochloride

SKU: A0191

Category: Non Fluorescent Detection & Chromogene Detection

Synonyms: Neurobiotin; 111822-45-8
CAS-Number: C₁₂H₂₃ClN₄O₂S
Molecular Formula: 322.85
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥95% (TLC)
Identity: 1H-NMR
Appearance: Solid

Properties

Solvents: water, DMSO

Short Term Storage: +4°C
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
Handling Advice: Protect from light and moisture.
Long Term Storage: -20°C
Shipping: AMBIENT

Transportation: Not dangerous goods

Description: Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.
InChi: InChI=1S/C12H22N4O2S.ClH/c13-5-6-14-10(17)4-2-1-3-9-11-8(7-19-9)15-12(18)16-11
References: (1) J.M.Kurner, O.S.Wolfbeis, I.Klimant: Anal Chem 74, 2151 (2002) , (2) C.J.Wong : J Comp Neurol 383, 18-41 (1997) , (3) R.K.Garlick, R.W. Giese: J Biol Chem 263, 210-215 (1988)
InChi Key: UWYKXZBFDOWDHO-GRIHUTHFSA-N
Smiles: Cl.[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2

Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.

SKU: A0191 Category: Non Fluorescent Detection & Chromogene Detection

Additional information

Additional information

Synonyms	Neurobiotin
Purity	≥95% (TLC)
Appearance	Solid
CAS-Number	111822-45-8
Molecular Formula	C12H23ClN4O2S
Molecular Weight	322.85
Identity	1H-NMR
Solvents	water, DMSO
Smiles	Cl.[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2
InChi Key	UWYKXZBFDOWDHO-GRIHUTHFSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	(1) J.M.Kurner, O.S.Wolfbeis, I.Klimant: Anal Chem 74, 2151 (2002), (2) C.J.Wong : J Comp Neurol 383, 18-41 (1997), (3) R.K.Garlick, R.W. Giese: J Biol Chem 263, 210-215 (1988)
InChi	InChI=1S/C12H22N4O2S.ClH/c13-5-6-14-10(17)4-2-1-3-9-11-8(7-19-9)15-12(18)16-11
Quantity	50 mg, 1 g, Bulk