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    N-(2-Aminoethyl)biotinamide hydrochloride

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      N-(2-Aminoethyl)biotinamide hydrochloride

      SKU
      A0191

      Category: Non Fluorescent Detection & Chromogene Detection

      Synonyms
      Neurobiotin
      111822-45-8
      CAS-Number
      C12H23ClN4O2S
      Molecular Formula
      322.85
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥95% (TLC)
      Identity
      1H-NMR
      Appearance
      Solid

      Properties

      Solvents
      water, DMSO

      Downloads

      Safety Data Sheet
      CDX A0191 MSDS_V1.2.pdf
      Short Term Storage
      +4°C
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Handling Advice
      Protect from light and moisture.
      Long Term Storage
      -20°C
      Shipping
      AMBIENT
      Transportation
      Not dangerous goods
      Description
      Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.
      InChi
      InChI=1S/C12H22N4O2S.ClH/c13-5-6-14-10(17)4-2-1-3-9-11-8(7-19-9)15-12(18)16-11
      References
      (1) J.M.Kurner, O.S.Wolfbeis, I.Klimant: Anal Chem 74, 2151 (2002) , (2) C.J.Wong : J Comp Neurol 383, 18-41 (1997) , (3) R.K.Garlick, R.W. Giese: J Biol Chem 263, 210-215 (1988)
      InChi Key
      UWYKXZBFDOWDHO-GRIHUTHFSA-N
      Smiles
      Cl.[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2

      Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.

      SKU: A0191 Category: Non Fluorescent Detection & Chromogene Detection
      • Additional information

      Additional information

      Synonyms

      Neurobiotin

      Purity

      ≥95% (TLC)

      Appearance

      Solid

      CAS-Number

      111822-45-8

      Molecular Formula

      C12H23ClN4O2S

      Molecular Weight

      322.85

      Identity

      1H-NMR

      Solvents

      water, DMSO

      Smiles

      Cl.[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2

      InChi Key

      UWYKXZBFDOWDHO-GRIHUTHFSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Transportation

      Not dangerous goods

      References

      (1) J.M.Kurner, O.S.Wolfbeis, I.Klimant: Anal Chem 74, 2151 (2002), (2) C.J.Wong : J Comp Neurol 383, 18-41 (1997), (3) R.K.Garlick, R.W. Giese: J Biol Chem 263, 210-215 (1988)

      InChi

      InChI=1S/C12H22N4O2S.ClH/c13-5-6-14-10(17)4-2-1-3-9-11-8(7-19-9)15-12(18)16-11

      Quantity

      50 mg, 1 g, Bulk

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