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    NBD-amine

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    NBD-amine

    SKU
    A0176

    Category: Fluorescent Detection

    Synonyms
    7-Amino-NBD , 7-Amino-4-nitro-2,1,3-benzoxadiazole , 7-Nitro-4-aminobenzofurazan , ABF
    10199-91-4
    CAS-Number
    C6H4N4O3
    Molecular Formula
    180.12
    Molecular Weight

    • Product Data
    • Handling
    • Safety Information
    • Details

    Specifications

    Purity
    ≥99% (HPLC)
    Identity
    1H-NMR
    Appearance
    Orange to brown powder

    Properties

    Density
    1.684 g/cm3
    Refractive Index
    1.745
    Optical Activity
    -7.7° (c=0.045, methanol)
    Melting Point
    237 °C
    Solvents
    methanol

    Downloads

    Safety Data Sheet
    CDX A0176 MSDS.pdf
    Short Term Storage
    +4°C
    Use / Stability
    Stable for at least 2 years after receipt when stored at -20°C.
    Handling Advice
    Protect from light and moisture.
    Long Term Storage
    -20°C
    Shipping
    AMBIENT
    Transportation
    Not dangerous goods
    Signal word
    Warning
    GHS Symbol
    GHS07
    Precautionary statements
    P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362
    Hazard statements
    H315, H319
    Description
    Fluorogenic amine. Building block and reagent for synthesis of fluorescent probes. Used for the preparation of fluorogenic substrates, chemosensors and probes, in which NBD-amine is the high fluoresence component after release. Shows constant fluorescence intensity from pH2-9. Spectral data: Ex=472nm, Em=555nm (TRIS buffer, pH7.8)
    InChi
    InChI=1/C6H4N4O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H,7H2
    References
    (1) E. Sato, et al., Chem. Pharm. Bull. 32, 336 (1984) , (2) S. Uchiyama, et al., J. Chem. Soc. Perkin Trans. 2, 2165 (1998) , (3) H. Ikeda, et al., Org. Biomol. Chem. 3, 4262 (2005) , (4) W. Jiang, et al., Angew. Chem. Int. Ed. 46, 8445 (2007) , (5) B. Heyne, et al., Org. Biomol. Chem. 6, 354 (2008) , (6) G. Zhou, et al., Tetrahedron 69, 867 (2013)
    InChi Key
    YXKOGLINWAPXPE-UHFFFAOYSA-N
    Smiles
    NC1=CC=C(C2=NON=C12)[N+]([O-])=O

    Fluorogenic amine. Building block and reagent for synthesis of fluorescent probes. Used for the preparation of fluorogenic substrates, chemosensors and probes, in which NBD-amine is the high fluoresence component after release. Shows constant fluorescence intensity from pH2-9. Spectral data: Ex=472nm, Em=555nm (TRIS buffer, pH7.8)

    SKU: A0176 Category: Fluorescent Detection
    • Additional information

    Additional information

    Synonyms

    7-Amino-NBD, 7-Amino-4-nitro-2,1,3-benzoxadiazole, 7-Nitro-4-aminobenzofurazan, ABF

    Purity

    ≥99% (HPLC)

    Appearance

    Orange to brown powder

    CAS-Number

    10199-91-4

    Molecular Formula

    C6H4N4O3

    Molecular Weight

    180.12

    Identity

    1H-NMR

    Solvents

    methanol

    Melting Point

    237 °C

    Optical Activity

    -7.7° (c=0.045, methanol)

    Refractive Index

    1.745

    Density

    1.684 g/cm3

    Smiles

    NC1=CC=C(C2=NON=C12)[N+]([O-])=O

    InChi Key

    YXKOGLINWAPXPE-UHFFFAOYSA-N

    Shipping

    AMBIENT

    Short Term Storage

    +4°C

    Long Term Storage

    -20°C

    Handling Advice

    Protect from light and moisture.

    Use / Stability

    Stable for at least 2 years after receipt when stored at -20°C.

    Hazard statements

    H315, H319

    Precautionary statements

    P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362

    GHS Symbol

    GHS07

    Signal word

    Warning

    Transportation

    Not dangerous goods

    References

    (1) E. Sato, et al., Chem. Pharm. Bull. 32, 336 (1984), (2) S. Uchiyama, et al., J. Chem. Soc. Perkin Trans. 2, 2165 (1998), (3) H. Ikeda, et al., Org. Biomol. Chem. 3, 4262 (2005), (4) W. Jiang, et al., Angew. Chem. Int. Ed. 46, 8445 (2007), (5) B. Heyne, et al., Org. Biomol. Chem. 6, 354 (2008), (6) G. Zhou, et al., Tetrahedron 69, 867 (2013)

    InChi

    InChI=1/C6H4N4O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H,7H2

    Quantity

    100 mg, 500 mg, Bulk

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