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    NBD-amine

    Available from stock

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      NBD-amine

      SKU
      A0176

      Categories: Fluorescent Detection, Fluorescent Detection

      Synonyms
      7-Amino-NBD , 7-Amino-4-nitro-2,1,3-benzoxadiazole , 7-Nitro-4-aminobenzofurazan , ABF
      10199-91-4
      CAS-Number
      C6H4N4O3
      Molecular Formula
      180.12
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥99% (HPLC)
      Appearance
      Orange to brown powder
      Identity
      1H-NMR

      Properties

      Solvents
      methanol
      Melting Point
      237 °C
      Optical Activity
      -7.7° (c=0.045, methanol)
      Refractive Index
      1.745
      Density
      1.684 g/cm3

      Documentation

      Safety Data Sheet (SDS)
      CDX A0176 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H315, H319
      Precautionary statements
      P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      Fluorogenic amine. Building block and reagent for synthesis of fluorescent probes. Used for the preparation of fluorogenic substrates, chemosensors and probes, in which NBD-amine is the high fluoresence component after release. Shows constant fluorescence intensity from pH2-9. Spectral data: Ex=472nm, Em=555nm (TRIS buffer, pH7.8)
      Smiles
      NC1=CC=C(C2=NON=C12)[N+]([O-])=O
      InChi Key
      YXKOGLINWAPXPE-UHFFFAOYSA-N
      References
      (1) E. Sato, et al., Chem. Pharm. Bull. 32, 336 (1984) , (2) S. Uchiyama, et al., J. Chem. Soc. Perkin Trans. 2, 2165 (1998) , (3) H. Ikeda, et al., Org. Biomol. Chem. 3, 4262 (2005) , (4) W. Jiang, et al., Angew. Chem. Int. Ed. 46, 8445 (2007) , (5) B. Heyne, et al., Org. Biomol. Chem. 6, 354 (2008) , (6) G. Zhou, et al., Tetrahedron 69, 867 (2013)
      InChi
      InChI=1/C6H4N4O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H,7H2

      Fluorogenic amine. Building block and reagent for synthesis of fluorescent probes. Used for the preparation of fluorogenic substrates, chemosensors and probes, in which NBD-amine is the high fluoresence component after release. Shows constant fluorescence intensity from pH2-9. Spectral data: Ex=472nm, Em=555nm (TRIS buffer, pH7.8)

      SKU: A0176 Categories: Fluorescent Detection, Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      7-Amino-NBD, 7-Amino-4-nitro-2,1,3-benzoxadiazole, 7-Nitro-4-aminobenzofurazan, ABF

      Purity

      ≥99% (HPLC)

      Appearance

      Orange to brown powder

      CAS-Number

      10199-91-4

      Molecular Formula

      C6H4N4O3

      Molecular Weight

      180.12

      Identity

      1H-NMR

      Solvents

      methanol

      Melting Point

      237 °C

      Optical Activity

      -7.7° (c=0.045, methanol)

      Refractive Index

      1.745

      Density

      1.684 g/cm3

      Smiles

      NC1=CC=C(C2=NON=C12)[N+]([O-])=O

      InChi Key

      YXKOGLINWAPXPE-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H315, H319

      Precautionary statements

      P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) E. Sato, et al., Chem. Pharm. Bull. 32, 336 (1984), (2) S. Uchiyama, et al., J. Chem. Soc. Perkin Trans. 2, 2165 (1998), (3) H. Ikeda, et al., Org. Biomol. Chem. 3, 4262 (2005), (4) W. Jiang, et al., Angew. Chem. Int. Ed. 46, 8445 (2007), (5) B. Heyne, et al., Org. Biomol. Chem. 6, 354 (2008), (6) G. Zhou, et al., Tetrahedron 69, 867 (2013)

      InChi

      InChI=1/C6H4N4O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H,7H2

      Quantity

      100 mg, 500 mg, Bulk

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