Available from stock

NBD-amine

SKU: A0176

Categories: Fluorescent Detection, Fluorescent Detection

Synonyms: 7-Amino-NBD , 7-Amino-4-nitro-2,1,3-benzoxadiazole , 7-Nitro-4-aminobenzofurazan , ABF; 10199-91-4
CAS-Number: C₆H₄N₄O₃
Molecular Formula: 180.12
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥99% (HPLC)
Appearance: Orange to brown powder
Identity: 1H-NMR

Properties

Solvents: methanol
Melting Point: 237 °C
Optical Activity: -7.7° (c=0.045, methanol)
Refractive Index: 1.745
Density: 1.684 g/cm3

Documentation

Safety Data Sheet (SDS): CDX A0176 MSDS.pdf

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H315, H319
Precautionary statements: P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: Fluorogenic amine. Building block and reagent for synthesis of fluorescent probes. Used for the preparation of fluorogenic substrates, chemosensors and probes, in which NBD-amine is the high fluoresence component after release. Shows constant fluorescence intensity from pH2-9. Spectral data: Ex=472nm, Em=555nm (TRIS buffer, pH7.8)
Smiles: NC1=CC=C(C2=NON=C12)[N+]([O-])=O
InChi Key: YXKOGLINWAPXPE-UHFFFAOYSA-N
References: (1) E. Sato, et al., Chem. Pharm. Bull. 32, 336 (1984) , (2) S. Uchiyama, et al., J. Chem. Soc. Perkin Trans. 2, 2165 (1998) , (3) H. Ikeda, et al., Org. Biomol. Chem. 3, 4262 (2005) , (4) W. Jiang, et al., Angew. Chem. Int. Ed. 46, 8445 (2007) , (5) B. Heyne, et al., Org. Biomol. Chem. 6, 354 (2008) , (6) G. Zhou, et al., Tetrahedron 69, 867 (2013)
InChi: InChI=1/C6H4N4O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H,7H2

Fluorogenic amine. Building block and reagent for synthesis of fluorescent probes. Used for the preparation of fluorogenic substrates, chemosensors and probes, in which NBD-amine is the high fluoresence component after release. Shows constant fluorescence intensity from pH2-9. Spectral data: Ex=472nm, Em=555nm (TRIS buffer, pH7.8)

SKU: A0176 Categories: Fluorescent Detection, Fluorescent Detection

Additional information

Additional information

Synonyms	7-Amino-NBD, 7-Amino-4-nitro-2,1,3-benzoxadiazole, 7-Nitro-4-aminobenzofurazan, ABF
Purity	≥99% (HPLC)
Appearance	Orange to brown powder
CAS-Number	10199-91-4
Molecular Formula	C6H4N4O3
Molecular Weight	180.12
Identity	1H-NMR
Solvents	methanol
Melting Point	237 °C
Optical Activity	-7.7° (c=0.045, methanol)
Refractive Index	1.745
Density	1.684 g/cm3
Smiles	NC1=CC=C(C2=NON=C12)[N+]([O-])=O
InChi Key	YXKOGLINWAPXPE-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H315, H319
Precautionary statements	P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) E. Sato, et al., Chem. Pharm. Bull. 32, 336 (1984), (2) S. Uchiyama, et al., J. Chem. Soc. Perkin Trans. 2, 2165 (1998), (3) H. Ikeda, et al., Org. Biomol. Chem. 3, 4262 (2005), (4) W. Jiang, et al., Angew. Chem. Int. Ed. 46, 8445 (2007), (5) B. Heyne, et al., Org. Biomol. Chem. 6, 354 (2008), (6) G. Zhou, et al., Tetrahedron 69, 867 (2013)
InChi	InChI=1/C6H4N4O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H,7H2
Quantity	100 mg, 500 mg, Bulk