Specifications
- Purity
- ≥99.0% (N)
- Appearance
- Off-white solid
- Identity
- 1H-NMR
Properties
- Solvents
- water, methanol, DMSO, DMF
- Melting Point
- 310-315° C (dec.)
Available from stock
SPQ
- SKU
- M0051
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- 6-Methoxy-N-(3-sulfopropyl)quinolinium , 3-(6Methoxyquinolin-1-ium-1-yl)propane-1-sulfonate , 6-M-Spq
- 83907-40-8
- CAS-Number
- C13H15NO4S
- Molecular Formula
- 281.33
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H315, H319, H335
- Precautionary statements
- P261, P280, P305+P351+P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Fluorescent dye to examine and measure membrane chloride transport mechanisms. The fluorescence of SPQ is specifically quenched by chloride via collision. Therefore, the chloride concentration is measured by monitoring the degree of fluorescence decrease. Spectral data: Spectral data: &lambda|ex=~344, &lambda|em=~443.
- Smiles
- O=S(CCC[N+]1=CC=CC2=CC(OC)=CC=C21)([O-])=O
- InChi Key
- ZVDGOJFPFMINBM-UHFFFAOYSA-N
- References
- (1) O.S. Wolfbeis & E. Urbano , J. Heterocycl. Chem. 19, 841 (1982) , (2) O.S. Wolfbeis & E. Urbano , Fresenius’ Z. Anal. Chem. 314, 577 (1983) , (3) N.P. Illsley A.S. Verkman , Biochemistry 26, 1215 (1987) , (4) R. Krapf, et al. , Anal. Biochem. 169, 142 (1988) , (5) G. Cabrini , Appl. Fluoresc. Technol. 1, 11 (1989) , (6) A.S. Verkman, et al. , Biochemistry 28, 4240 (1989) , (7) M. Vasseur, et al. , Am. J. Physiol. 264, C27 (1993) , (8) B. Pilas & G. Durack , Cytometry 28, 316 (1997) , (9) R. Shingles, et al. , J. Bioenerg. Biomembr. 29, 611 (1997)
Fluorescent dye to examine and measure membrane chloride transport mechanisms. The fluorescence of SPQ is specifically quenched by chloride via collision. Therefore, the chloride concentration is measured by monitoring the degree of fluorescence decrease. Spectral data: Spectral data: &lambda|ex=~344, &lambda|em=~443.
Additional information
| Synonyms | 6-Methoxy-N-(3-sulfopropyl)quinolinium, 3-(6Methoxyquinolin-1-ium-1-yl)propane-1-sulfonate, 6-M-Spq |
|---|---|
| Purity | ≥99.0% (N) |
| Appearance | Off-white solid |
| CAS-Number | 83907-40-8 |
| Molecular Formula | C13H15NO4S |
| Molecular Weight | 281.33 |
| Identity | 1H-NMR |
| Solvents | water, methanol, DMSO, DMF |
| Melting Point | 310-315° C (dec.) |
| Smiles | O=S(CCC[N+]1=CC=CC2=CC(OC)=CC=C21)([O-])=O |
| InChi Key | ZVDGOJFPFMINBM-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P280, P305+P351+P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) O.S. Wolfbeis & E. Urbano, J. Heterocycl. Chem. 19, 841 (1982), (2) O.S. Wolfbeis & E. Urbano, Fresenius’ Z. Anal. Chem. 314, 577 (1983), (3) N.P. Illsley A.S. Verkman, Biochemistry 26, 1215 (1987), (4) R. Krapf, et al., Anal. Biochem. 169, 142 (1988), (5) G. Cabrini, Appl. Fluoresc. Technol. 1, 11 (1989), (6) A.S. Verkman, et al., Biochemistry 28, 4240 (1989), (7) M. Vasseur, et al., Am. J. Physiol. 264, C27 (1993), (8) B. Pilas & G. Durack, Cytometry 28, 316 (1997), (9) R. Shingles, et al., J. Bioenerg. Biomembr. 29, 611 (1997) |
| Quantity | 250 mg, 1 g, Bulk |
