Specifications
- Purity
- ≥99% (TLC)
- Appearance
- White to off-white powder
- Identity
- IR
Properties
- Solvents
- water
- Melting Point
- 273 °C (dec.) (lit.)
- Optical Activity
- [α]20/D -74° to -77°, c=1 in H2O
Downloads
- Safety Data Sheet
- CDX T0254 MSDS.pdf
Category: Amino Acids, Peptides, Proteins
Trans-4-Hydroxy-L-proline is a non-essential amino acid and a natural constituent of animal structural proteins such as collagen and elastin. It is commonly used as a chiral building block in the organic synthesis of various compounds, such as neuroexcitatory kainoids and antifungal echinocandins. It has been found in many bacterial secondary metabolites, including echinocandins.
Synonyms | (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp, (S)-(-)-trans-4-Hydroxyproline, 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic acid, NSC 46704, H-Hyp-OH, L-Hydroxypyroline |
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Purity | ≥99% (TLC) |
Appearance | White to off-white powder |
CAS-Number | 51-35-4 |
Molecular Formula | C5H9NO3 |
Molecular Weight | 131.13 |
Identity | IR |
Solvents | water |
Melting Point | 273 °C (dec.) (lit.) |
Optical Activity | [α]20/D -74° to -77°, c=1 in H2O |
Smiles | O[C@H]1CN[C@H](C(O)=O)C1 |
InChi Key | PMMYEEVYMWASQN-SYPWQXSBSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | RT |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
Transportation | Not dangerous goods |
References | (1) P. Remuzon, et al., Tetrahedron 44, 13803 (1996), (2) M.J. Blanco & F.J. Sardina, J. Org. Chem. 61, 4748 (1996), (3) J.E. Baldwin, et al., Bioorg. Med. Chem. Lett. 10, 1927 (2000), (4) J.F. Poisson, et al., J. Org. Chem. 70, 10860 (2005), (5) G. Cremonesi, et al., J. Org. Chem. 75, 2010 (2010) |
InChi | InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4?/m1/s1 |
Quantity | 25 g, 100 g, Bulk |