Specifications
- Purity
- ≥97% (HPLC)
- Appearance
- White to off-white solid
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform
Downloads
- Safety Data Sheet
- CDX D0390 MSDS.pdf
Category: API's & Intermediates
Major naproxen demethylation metabolite. Naproxen demethylation is mediated primarily by CYP2C9. Can be used for assaying naproxen metabolites.
Synonyms | (S)-6-Hydroxy-α-methyl-2-naphthaleneacetic acid, (S)-6-O-Desmethylnaproxen |
---|---|
Purity | ≥97% (HPLC) |
Appearance | White to off-white solid |
CAS-Number | 52079-10-4 |
Molecular Formula | C13H12O3 |
Molecular Weight | 216.2 |
Identity | 1H-NMR |
Solvents | chloroform |
Smiles | C[C@H](C(O)=O)C1=CC2=CC=C(O)C=C2C=C1 |
InChi Key | XWJUDDGELKXYNO-QMMMGPOBSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Hazard statements | H302-H317-H400 |
Precautionary statements | P273-P280 |
GHS Symbol | GHS07+GHS09 |
Signal word | Warning |
RIDADR | UN3077 9 |
Transportation | Excepted Quantities |
References | (1) C.H. Kiang, et al.: Drug Metab. Dispos. 17, 43 (1989), (2) A. Rettie, et al.: Chem. Res. Toxicol. 5, 54 (1992), (3) T.B. Vree, et al.: Br. J. Clin. Pharmacol. 35, 467 (1993), (4) T.B. Vree, et al.: Biopharm. Drug Dispos. 14, 491 (1993), (5) P. Bonnabry, et al.: Eur. J. Clin. Pharmacol. 49, 305 (1996), (6) J.O. Miners, et al.: Biochem. Pharmacol. 51, 1003 (1996), (7) T.S. Tracy, et al.: Eur. J. Clin. Pharmacol. 52, 293 (1997), (8) S. Rao, et al.: J. Med. Chem. 43, 2789 (2000), (9) L. Wei, et al.: Mol. Pharmacol. 72, 1280 (2007), (10) K.C. Duggan, et al.: J. Biol. Chem. 285, 34950 (2010) |
InChi | InChI=1S/C13H12O3/c1-8(13(15)16)9-2-3-11-7-12(14)5-4-10(11)6-9/h2-8,14H,1H3,(H,15,16)/t8-/m0/s1 |
Quantity | 10 mg, 50 mg, Bulk |