Available from stock
Category: Phytochemicals
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Adenosine is a purine nucleoside composed of adenine and ribose linked by a glycosidic linkage. Adenosine is a key endogenous neurotransmitter that regulates tissue function in an anti- and pro-inflammatory manner by activating four G-protein-coupled adenosine receptors: A1, A2A, A2B and A3, which serve diverse roles related to smooth muscle tone, central nervous system regulation and cardiac function. Cells of the immune system express these receptors and are responsive to the modulatory effects of adenosine in an inflammatory environment. Adenosine is a precursor for adenosine 5’-monophosphate, adenosine 5’-diphosphate, adenosine 5’-triphosphate and cyclic AMP.
| Synonyms | 9-β-D-Ribofuranosyladenine, Adenine riboside, Adenine-9-β-D-ribofuranoside, NSC 7652 |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off white powder |
| CAS-Number | 58-61-7 |
| Molecular Formula | C10H13N5O4 |
| Molecular Weight | 267.24 |
| Identity | 1H-NMR |
| Solvents | 1M NH4OH, water (7 mg/ml), DMSO (75 mM), ethanol (insoluble) |
| Melting Point | 234-236 °C(lit.) |
| Optical Activity | -70°, c = 2 in 5% NaOH |
| Smiles | C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O |
| InChi Key | OIRDTQYFTABQOQ-KQYNXXCUSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Transportation | Not dangerous goods |
| References | "(1) G. Hasko & B.N. Cronstein, Trends Immunol. 25, 33 (2004), (2) K.A. Jacobson & Z.G. Gao, Nat. Rev. Drug Discov. 5, 247 (2006) (Review), (3) G. Hasko, et al., Nat. Rev. Drug Discov. 7, 759 (2008) (Review), (4) S. Nakav, et al., PLoS One 3, e2107 (2008) |
| Quantity | 50 g, 100 g, Bulk |
Aloe-Emodine
