Available from stock

Ampicilline sodium salt

SKU: A0313

Category: Antibiotics

Synonyms: D-(-)-α-Aminobenzylpenicillin sodium salt; 69-52-3
CAS-Number: C₁₆H₁₈N₃NaO₄S
Molecular Formula: 371.39
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: min 85% (HPLC)
Appearance: White to slight yellow powder
Identity: 1H-NMR

Properties

Solvents: Soluble in water (20 mg/ml). Soluble in DMSO or DMF (both 10mg/ml).
Melting Point: 215 °C (dec.) (lit.)

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: +4°C
Handling Advice: Very hygroscopic. Store under inert gas.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Hazard statements: H317-H334
Precautionary statements: P261-P280-P342 + P311
GHS Symbol: GHS08
Signal word: Danger
Transportation: Not dangerous goods

Description: Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria. Formulations containing ampicillin have been used to treat a variety of bacterial infections. This is a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it. Ampicillin is widely used in cell culture as a selective agent for transformed cells expressing β-lactamase. Can also be used as reference material.
Smiles: O=C1[C@@H](NC([C@H](N)C2=CC=CC=C2)=O)[C@]3([H])N1[C@@H](C([O-])=O)C(C)(C)S3.[Na+]
InChi Key: KLOHDWPABZXLGI-YWUHCJSESA-M
References: (1) E. Lockey, et al., Br. J. Clin. Pract. 16, 13 (1962) , (2) H.J. Rogers & J. Mandelstam, Biochem. J. 84, 299 (1962) , (3) D.M. Campoli-Richards & R.N. Brogden, Drugs 33, 577 (1987) (Review) , (4) P.I. Rafailidis, et al., Drugs 67, 1829 (2007) (Review) , (5) E.G. Awji, et al., J. Vet. Med. Sci. 74, 1091 (2012)

Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria. Formulations containing ampicillin have been used to treat a variety of bacterial infections. This is a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it. Ampicillin is widely used in cell culture as a selective agent for transformed cells expressing β-lactamase. Can also be used as reference material.

SKU: A0313 Category: Antibiotics

Additional information

Additional information

Synonyms	D-(-)-α-Aminobenzylpenicillin sodium salt
Purity	min 85% (HPLC)
Appearance	White to slight yellow powder
CAS-Number	69-52-3
Molecular Formula	C16H18N3NaO4S
Molecular Weight	371.39
Identity	1H-NMR
Solvents	Soluble in water (20 mg/ml). Soluble in DMSO or DMF (both 10mg/ml).
Melting Point	215 °C (dec.) (lit.)
Smiles	O=C1[C@@H](NC([C@H](N)C2=CC=CC=C2)=O)[C@]3([H])N1[C@@H](C([O-])=O)C(C)(C)S3.[Na+]
InChi Key	KLOHDWPABZXLGI-YWUHCJSESA-M
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	+4°C
Handling Advice	Very hygroscopic. Store under inert gas.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H317-H334
Precautionary statements	P261-P280-P342 + P311
GHS Symbol	GHS08
Signal word	Danger
Transportation	Not dangerous goods
References	(1) E. Lockey, et al., Br. J. Clin. Pract. 16, 13 (1962), (2) H.J. Rogers & J. Mandelstam, Biochem. J. 84, 299 (1962), (3) D.M. Campoli-Richards & R.N. Brogden, Drugs 33, 577 (1987) (Review), (4) P.I. Rafailidis, et al., Drugs 67, 1829 (2007) (Review), (5) E.G. Awji, et al., J. Vet. Med. Sci. 74, 1091 (2012)
Quantity	5 g, 25 g, Bulk