Specifications
- Purity
- min 85% (HPLC)
- Appearance
- White to slight yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in water (20 mg/ml). Soluble in DMSO or DMF (both 10mg/ml).
- Melting Point
- 215 °C (dec.) (lit.)
Category: Antibiotics
Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria. Formulations containing ampicillin have been used to treat a variety of bacterial infections. This is a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it. Ampicillin is widely used in cell culture as a selective agent for transformed cells expressing β-lactamase. Can also be used as reference material.
Synonyms | D-(-)-α-Aminobenzylpenicillin sodium salt |
---|---|
Purity | min 85% (HPLC) |
Appearance | White to slight yellow powder |
CAS-Number | 69-52-3 |
Molecular Formula | C16H18N3NaO4S |
Molecular Weight | 371.39 |
Identity | 1H-NMR |
Solvents | Soluble in water (20 mg/ml). Soluble in DMSO or DMF (both 10mg/ml). |
Melting Point | 215 °C (dec.) (lit.) |
Smiles | O=C1[C@@H](NC([C@H](N)C2=CC=CC=C2)=O)[C@]3([H])N1[C@@H](C([O-])=O)C(C)(C)S3.[Na+] |
InChi Key | KLOHDWPABZXLGI-YWUHCJSESA-M |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | +4°C |
Handling Advice | Very hygroscopic. Store under inert gas. |
Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Hazard statements | H317-H334 |
Precautionary statements | P261-P280-P342 + P311 |
GHS Symbol | GHS08 |
Signal word | Danger |
Transportation | Not dangerous goods |
References | (1) E. Lockey, et al., Br. J. Clin. Pract. 16, 13 (1962), (2) H.J. Rogers & J. Mandelstam, Biochem. J. 84, 299 (1962), (3) D.M. Campoli-Richards & R.N. Brogden, Drugs 33, 577 (1987) (Review), (4) P.I. Rafailidis, et al., Drugs 67, 1829 (2007) (Review), (5) E.G. Awji, et al., J. Vet. Med. Sci. 74, 1091 (2012) |
Quantity | 5 g, 25 g, Bulk |