Diclofenac acid

SKU: D0147

Category: API's & Intermediates

Synonyms: Voltaren , Diclofenacum , 2-[(2,6-Dichlorophenyl)amino]-benzeneacetic acid; 15307-86-5
CAS-Number: C₁₄H₁₁Cl₂NO₂
Molecular Formula: 296.15
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Identity: 1H-NMR
Appearance: White powder

Properties

Melting Point: 156-158 °C
Solvents: water (237 mg/L)

Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at RT.
Long Term Storage: RT
Short Term Storage: RT
Shipping: AMBIENT

Transportation: Packing Group III
RIDADR: UN2811 6.1
Signal word: Danger
GHS Symbol: GHS06
Precautionary statements: P270, P264, P301+P310+P330, P405, P501
Hazard statements: H301

Description: Nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain. The primary mechanism responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Can be used as a reference compound.
InChi: InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
References: (1) J.T. Gan, et al.: Curr. Med. Res. Opin. 26, 1715 (2010) (Review)
InChi Key: DCOPUUMXTXDBNB-UHFFFAOYSA-N
Smiles: ClC1=C(NC2=CC=CC=C2CC(O)=O)C(Cl)=CC=C1

Nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain. The primary mechanism responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Can be used as a reference compound.

SKU: D0147 Category: API's & Intermediates

Additional information

Additional information

Synonyms	Voltaren, Diclofenacum, 2-[(2,6-Dichlorophenyl)amino]-benzeneacetic acid
Purity	≥98% (HPLC)
Appearance	White powder
CAS-Number	15307-86-5
Molecular Formula	C14H11Cl2NO2
Molecular Weight	296.15
Identity	1H-NMR
Solvents	water (237 mg/L)
Melting Point	156-158 °C
Smiles	ClC1=C(NC2=CC=CC=C2CC(O)=O)C(Cl)=CC=C1
InChi Key	DCOPUUMXTXDBNB-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	RT
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at RT.
Hazard statements	H301
Precautionary statements	P270, P264, P301+P310+P330, P405, P501
GHS Symbol	GHS06
Signal word	Danger
RIDADR	UN2811 6.1
Transportation	Packing Group III
References	(1) J.T. Gan, et al.: Curr. Med. Res. Opin. 26, 1715 (2010) (Review)
InChi	InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
Quantity	5 g, 25 g, 100 g, Bulk