Available from stock

Diclofenac Impurity C

SKU: D1227

Category: API's & Intermediates

Synonyms: Diclofenac impurity C (PhEur), o-(2,6-Dichloranilino)-benzylalkohol, (2-[(2,6-Dichlorophenyl)amino]phenyl)methanol; 27204-57-5
CAS-Number: C₁₃H₁₁Cl₂NO
Molecular Formula: 268.14
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: White to off-white powder or crystals
Identity: 1H-NMR
Water content (K.F.): ≤0.5%

Properties

Solvents: DMSO

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H319
Precautionary statements: P305 + P351 + P338
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: Diclofenac Impurity C is a degradation product of and a regulatory impurity in the drug Diclofenac which is a non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat inflammation associated with arthritis and gout as well as other pain or inflammatory disorders. This product can be used as a working standard or secondary analytical reference standard. It can also be used as an organic building block and intermediate for synthesis.
Smiles: ClC1=C(NC2=CC=CC=C2CO)C(Cl)=CC=C1
InChi Key: HFLGAAAKRFLWLN-UHFFFAOYSA-N
References: (1) C. Martinez, et al., Appl. Cat. B Environ. 107, 110 (2011) , (2) X. Cheng, et al., J. Environm. Chem. Eng. 3, 1713 (2015) , (3) M. Azougagh, et al., Ann. Pharm. Fr. 74, 358 (2016) , (4) S. Orlandini, et al., J. Chromatogr. A 1466, 189 (2016) , (5) C. Caprini, et al., J. Pharm. Biomed. Anal. 149, 249 (2018) , (6) Y. Tateishi, et al., ACS Omega 5, 32608 (2020)
InChi: InChI=1S/C13H11Cl2NO/c14-10-5-3-6-11(15)13(10)16-12-7-2-1-4-9(12)8-17/h1-7,16-17H,8H2

Diclofenac Impurity C is a degradation product of and a regulatory impurity in the drug Diclofenac which is a non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat inflammation associated with arthritis and gout as well as other pain or inflammatory disorders. This product can be used as a working standard or secondary analytical reference standard. It can also be used as an organic building block and intermediate for synthesis.

SKU: D1227 Category: API's & Intermediates

Additional information

Additional information

Synonyms	Diclofenac impurity C (PhEur), o-(2,6-Dichloranilino)-benzylalkohol, (2-[(2,6-Dichlorophenyl)amino]phenyl)methanol
Purity	≥98% (HPLC)
Appearance	White to off-white powder or crystals
CAS-Number	27204-57-5
Molecular Formula	C13H11Cl2NO
Molecular Weight	268.14
Identity	1H-NMR
Solvents	DMSO
Smiles	ClC1=C(NC2=CC=CC=C2CO)C(Cl)=CC=C1
InChi Key	HFLGAAAKRFLWLN-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H319
Precautionary statements	P305 + P351 + P338
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) C. Martinez, et al., Appl. Cat. B Environ. 107, 110 (2011), (2) X. Cheng, et al., J. Environm. Chem. Eng. 3, 1713 (2015), (3) M. Azougagh, et al., Ann. Pharm. Fr. 74, 358 (2016), (4) S. Orlandini, et al., J. Chromatogr. A 1466, 189 (2016), (5) C. Caprini, et al., J. Pharm. Biomed. Anal. 149, 249 (2018), (6) Y. Tateishi, et al., ACS Omega 5, 32608 (2020)
InChi	InChI=1S/C13H11Cl2NO/c14-10-5-3-6-11(15)13(10)16-12-7-2-1-4-9(12)8-17/h1-7,16-17H,8H2
Quantity	50 mg, Bulk
cdx-Water content (K.F.)	≤0.5%