Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder or crystals
- Identity
- 1H-NMR
- Water content (K.F.)
- ≤1.0%
Properties
- Solvents
- DMSO, methanol (1mg/ml)
Available from stock
Ibuprofen Impurity K
- SKU
- I0303
Category: API's & Intermediates
- Synonyms
- (2RS)-2-(4-Formylphenyl)propionic acid, FPP
- 43153-07-7
- CAS-Number
- C10H10O3
- Molecular Formula
- 178.18
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H315 - H319 - H335
- Precautionary statements
- P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- The metabolite (2RS)-2-(4-Formylphenyl)propionic acid (Ibuprofen Impurity K) is a degradation product arising from oxidative and thermal treatments of Ibuprofen which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain from various conditions such as headache, dental pain or menstrual cramps. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2. This product can be used as a working standard or secondary analytical reference standard. It can also be used as an organic building block and intermediate for synthesis.
- Smiles
- OC(C(C)C1=CC=C(C([H])=O)C=C1)=O
- InChi Key
- IAXYHYOWEQQFMC-UHFFFAOYSA-N
- References
- (1) P.A. Asmus, et al., J. Chromatogr. A 331, 169 (1985) , (2) G. Caviglioli, et al., J. Pharm. Biomed. Anal. 30, 499 (2002) , (3) M. Gaydou, et al., JACS 139, 12161 (2017) , (4) Z. Han, et al., Chromatographia 80, 1353 (2017) , (5) G. Rubasinghege, et al., Water Res. 131, 22 (2018)
- InChi
- InChi=1S/C10H10O3/c1-7(10(12)13)9-4-2-8(6-11)3-5-9/h2-7H,1H3,(H,12,13)
The metabolite (2RS)-2-(4-Formylphenyl)propionic acid (Ibuprofen Impurity K) is a degradation product arising from oxidative and thermal treatments of Ibuprofen which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain from various conditions such as headache, dental pain or menstrual cramps. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2. This product can be used as a working standard or secondary analytical reference standard. It can also be used as an organic building block and intermediate for synthesis.
Additional information
| Synonyms | (2RS)-2-(4-Formylphenyl)propionic acid, FPP |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder or crystals |
| CAS-Number | 43153-07-7 |
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.18 |
| Identity | 1H-NMR |
| Solvents | DMSO, methanol (1mg/ml) |
| Smiles | OC(C(C)C1=CC=C(C([H])=O)C=C1)=O |
| InChi Key | IAXYHYOWEQQFMC-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315 – H319 – H335 |
| Precautionary statements | P261 – P264 – P271 – P280 – P302 + P352 – P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) P.A. Asmus, et al., J. Chromatogr. A 331, 169 (1985), (2) G. Caviglioli, et al., J. Pharm. Biomed. Anal. 30, 499 (2002), (3) M. Gaydou, et al., JACS 139, 12161 (2017), (4) Z. Han, et al., Chromatographia 80, 1353 (2017), (5) G. Rubasinghege, et al., Water Res. 131, 22 (2018) |
| InChi | InChi=1S/C10H10O3/c1-7(10(12)13)9-4-2-8(6-11)3-5-9/h2-7H,1H3,(H,12,13) |
| Quantity | 100 mg, 250 mg, Bulk |
| cdx-Water content (K.F.) | ≤1.0% |
