Available from stock

Glycitin

SKU: G0136

Category: Carbohydrates

Synonyms: 7-(β-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one , Glycitein-7-β-O-glucoside; 40246-10-4
CAS-Number: C₂₂H₂₂O₁₀
Molecular Formula: 446.40
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: White powder
Identity: 1H-NMR

Properties

Solvents: DMSO (20 mg/ml), DMF (20 mg/ml)

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: RT
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at RT.

Transportation: Not dangerous goods

Description: Glycitin is a natural isoflavone isolated from legumes, including soy and kudzu. It has been reported to have multiply biological functions, such as anti-inflammatory, antioxidant, antiobesity, anticardiovascular activity and promoting wound healing. Like other isoflavones, glycitin promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. Glycitin can be modified by the action of beta-glucosidases into the metabolite glycitein which has anti-inflammatory properties.
Smiles: OC(C=C1)=CC=C1C2=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=C(OC)C=C3C2=O
InChi Key: OZBAVEKZGSOMOJ-MIUGBVLSSA-N
References: (1) T. Uesugi, et al., Biol. Pharm. Bull. 24, 368 (2001) , (2) X.H. Li, et al., Acta Pharmacol. Sin. 26, 1081 (2005) , (3) Y. Zang, et al., Biosci. Biotechnol. Biochem. 79, 117 (2015) , (4) Y.M. Kim, et al., Phytother. Res. 29, 757 (2015) , (5) L. Zhang, et al., Exp. Ther. Med. 12, 3063 (2016) , (6) G.Y. Seo, et al., Exp. Mol. Med. 49, e302 (2017) , (7) Y. Chen, et al., Int. Immunopharmacol. 75, 105749 (2019)
InChi: InChI=1S/C22H22O10/c1-29-15-6-12-14(30-9-13(18(12)25)10-2-4-11(24)5-3-10)7-16(15)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1

Glycitin is a natural isoflavone isolated from legumes, including soy and kudzu. It has been reported to have multiply biological functions, such as anti-inflammatory, antioxidant, antiobesity, anticardiovascular activity and promoting wound healing. Like other isoflavones, glycitin promotes the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover. Glycitin can be modified by the action of beta-glucosidases into the metabolite glycitein which has anti-inflammatory properties.

SKU: G0136 Category: Carbohydrates

Additional information

Additional information

Synonyms	7-(β-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one, Glycitein-7-β-O-glucoside
Purity	≥98% (HPLC)
Appearance	White powder
CAS-Number	40246-10-4
Molecular Formula	C22H22O10
Molecular Weight	446.40
Identity	1H-NMR
Solvents	DMSO (20 mg/ml), DMF (20 mg/ml)
Smiles	OC(C=C1)=CC=C1C2=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=C(OC)C=C3C2=O
InChi Key	OZBAVEKZGSOMOJ-MIUGBVLSSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	RT
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at RT.
Transportation	Not dangerous goods
References	(1) T. Uesugi, et al., Biol. Pharm. Bull. 24, 368 (2001), (2) X.H. Li, et al., Acta Pharmacol. Sin. 26, 1081 (2005), (3) Y. Zang, et al., Biosci. Biotechnol. Biochem. 79, 117 (2015), (4) Y.M. Kim, et al., Phytother. Res. 29, 757 (2015), (5) L. Zhang, et al., Exp. Ther. Med. 12, 3063 (2016), (6) G.Y. Seo, et al., Exp. Mol. Med. 49, e302 (2017), (7) Y. Chen, et al., Int. Immunopharmacol. 75, 105749 (2019)
InChi	InChI=1S/C22H22O10/c1-29-15-6-12-14(30-9-13(18(12)25)10-2-4-11(24)5-3-10)7-16(15)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1
Quantity	25 mg, Bulk