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L-2,4-Diaminobutyric acid dihydrochloride

SKU: D0154

Category: Metabolites

Synonyms: (2S)-2,4-Diamino-butanoic acid dihydrochloride , H-Dab-OH; 1883-09-6
CAS-Number: C₄H₁₀N₂O₂ . ₂HCl
Molecular Formula: 118.1 . 72.9
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: Yellowish powder
Identity: 1H-NMR

Properties

Solvents: water
Melting Point: 195 °C
Optical Activity: [α]20/D +14.5±1.5°, c = 3.67% in H2O

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Hazard statements: H315-H318-H335
Precautionary statements: P261-P280-P305 + P351 + P338
GHS Symbol: GHS05+GHS07
Signal word: Danger
Transportation: Not dangerous goods

Description: Unnatural amino acid derivative. Pharmacological tool and potential chiral building block used as an internal standard for amino acid analysis. Suitable reagent used for the differentiation of ?-N-methylamino-L-alanine from the diamino acids by using HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS). Used in the quantification of neurotoxin ?-N-methylamino-L-alanine (BMAA) in seafood. It has been found to inhibit GABA transaminase (ABAT), producing elevated levels of GABA and to have an antitumor activity.
Smiles: [NH3+]CCC([NH3+])C(O)=O.[Cl-].[Cl-]
InChi Key: CKAAWCHIBBNLOJ-UHFFFAOYSA-N
References: (1) J.F. Riordan & R.W. Giese , Meth. Enzymol. 47, 31 (1977) , (2) P.M. Beart, et al.: Neurosci. Lett. 5, 193 (1977) , (3) G. Ronquist, et al.: J. Cancer Res. Clin. Oncol. 96, 259 (1980) , (4) P.J. Blind, et al.: Anticancer Res. 23, 1245 (2003) , (5) M.G. Thomas , J. Bacteriol. 191, 4594 (2009) , (6) S.A. Banack, et al.: Toxicon. 57, 730 (2011) , (7) L. Jiang, et al.: Sci. Rep. 4, 6931 (2014)
InChi: InChI=1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8

Unnatural amino acid derivative. Pharmacological tool and potential chiral building block used as an internal standard for amino acid analysis. Suitable reagent used for the differentiation of ?-N-methylamino-L-alanine from the diamino acids by using HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS). Used in the quantification of neurotoxin ?-N-methylamino-L-alanine (BMAA) in seafood. It has been found to inhibit GABA transaminase (ABAT), producing elevated levels of GABA and to have an antitumor activity.

SKU: D0154 Category: Metabolites

Additional information

Additional information

Synonyms	(2S)-2,4-Diamino-butanoic acid dihydrochloride, H-Dab-OH
Purity	≥98% (HPLC)
Appearance	Yellowish powder
CAS-Number	1883-09-6
Molecular Formula	C4H10N2O2 . 2HCl
Molecular Weight	118.1 . 72.9
Identity	1H-NMR
Solvents	water
Melting Point	195 °C
Optical Activity	[α]20/D +14.5±1.5°, c = 3.67% in H2O
Smiles	[NH3+]CCC([NH3+])C(O)=O.[Cl-].[Cl-]
InChi Key	CKAAWCHIBBNLOJ-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H315-H318-H335
Precautionary statements	P261-P280-P305 + P351 + P338
GHS Symbol	GHS05+GHS07
Signal word	Danger
Transportation	Not dangerous goods
References	(1) J.F. Riordan & R.W. Giese, Meth. Enzymol. 47, 31 (1977), (2) P.M. Beart, et al.: Neurosci. Lett. 5, 193 (1977), (3) G. Ronquist, et al.: J. Cancer Res. Clin. Oncol. 96, 259 (1980), (4) P.J. Blind, et al.: Anticancer Res. 23, 1245 (2003), (5) M.G. Thomas, J. Bacteriol. 191, 4594 (2009), (6) S.A. Banack, et al.: Toxicon. 57, 730 (2011), (7) L. Jiang, et al.: Sci. Rep. 4, 6931 (2014)
InChi	InChI=1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8
Quantity	1 g, 5 g, Bulk