Available from stock

Protodioscin

SKU: P0451

Category: Phytochemicals

Synonyms: NSC 698796; 55056-80-9
CAS-Number: C₅₁H₈₄O₂₂
Molecular Formula: 1049.2
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: White to off-white powder
Identity: 1H-NMR

Properties

Solvents: DMSO (20 mg/ml), DMF (5 mg/ml), ethanol (10 mg/ml)

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Transportation: Not dangerous goods

Description: Protodioscin is a steroidal saponin first isolated from plants, with anticancer, antihyperlipidemic, antioxidant, anti-inflammatory and neuroprotective properoteis. It displays cytotoxic, apoptosis incuding and antiproliferative activity against a range of cancer cells. Protodioscin has also been shown to have aphrodisiac properties.
Smiles: ###############################################################################################################################################################################################################################################################
InChi Key: LVTJOONKWUXEFR-UEZXSUPNSA-N
References: (1) K. Hu & X. Yao, Planta Med. 68, 297 (2002) , (2) K. Gauthaman, et al., Life Sci. 71, 1385 (2002) , (3) H. Hibasami, et al., Int. J. Mol. Med. 11, 23 (2003) , (4) T. Wang, et al., Planta Med. 76, 1642 (2010) , (5) X. Zhang, et al., Steroids 113, 52 (2016) , (6) M. Oyama, et al., Curr. Bioact. Compd. 13, 170 (2017) , (7) J.Y. Liu, et al., Apoptosis 22, 1454 (2017) , (8) J. Wu, et al., Pharmacol. Rep. 70, 139 (2018) , (9) C.L. Lin, et al., Cell Physiol. Biochem. 46, 322 (2018) , (10) K. Shu & Y. Zhang, Cell Stress Chaperones 24, 1091 (2019)
InChi: InChI=1S/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1

Protodioscin is a steroidal saponin first isolated from plants, with anticancer, antihyperlipidemic, antioxidant, anti-inflammatory and neuroprotective properoteis. It displays cytotoxic, apoptosis incuding and antiproliferative activity against a range of cancer cells. Protodioscin has also been shown to have aphrodisiac properties.

SKU: P0451 Category: Phytochemicals

Additional information

Additional information

Synonyms	NSC 698796
Purity	≥98% (HPLC)
Appearance	White to off-white powder
CAS-Number	55056-80-9
Molecular Formula	C51H84O22
Molecular Weight	1049.2
Identity	1H-NMR
Solvents	DMSO (20 mg/ml), DMF (5 mg/ml), ethanol (10 mg/ml)
Smiles	###############################################################################################################################################################################################################################################################
InChi Key	LVTJOONKWUXEFR-UEZXSUPNSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) K. Hu & X. Yao, Planta Med. 68, 297 (2002), (2) K. Gauthaman, et al., Life Sci. 71, 1385 (2002), (3) H. Hibasami, et al., Int. J. Mol. Med. 11, 23 (2003), (4) T. Wang, et al., Planta Med. 76, 1642 (2010), (5) X. Zhang, et al., Steroids 113, 52 (2016), (6) M. Oyama, et al., Curr. Bioact. Compd. 13, 170 (2017), (7) J.Y. Liu, et al., Apoptosis 22, 1454 (2017), (8) J. Wu, et al., Pharmacol. Rep. 70, 139 (2018), (9) C.L. Lin, et al., Cell Physiol. Biochem. 46, 322 (2018), (10) K. Shu & Y. Zhang, Cell Stress Chaperones 24, 1091 (2019)
InChi	InChI=1S/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1
Quantity	10 mg, Bulk