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    (+)-Bicuculline

    Available from stock

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      (+)-Bicuculline

      SKU
      B0239

      Category: Phytochemicals

      Synonyms
      (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one
      485-49-4
      CAS-Number
      C20H17NO6
      Molecular Formula
      367.35
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥99% (HPLC)
      Appearance
      Off-white to yellow powder
      Identity
      1H-NMR

      Properties

      Solvents
      chloroform
      Melting Point
      193-197 °C
      Optical Activity
      [α]20/D +126±6°, c = 1% in chloroform

      Documentation

      Safety Data Sheet (SDS)
      CDX B0239 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      +4°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Hazard statements
      H300, H311, H314, H331, H400
      Precautionary statements
      P261, P264, P273, P280, P301 + P310, P305 + P351 + P338
      GHS Symbol
      GHS05+GHS06+GHS09
      Signal word
      Danger
      RIDADR
      UN1544 6.1
      Transportation
      Excepted Quantities
      Description
      GABAA receptor antagonist.
      Smiles
      [H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12
      InChi Key
      IYGYMKDQCDOMRE-ZWKOTPCHSA-N
      References
      (1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997) , (2) S.W. Johnson et al.: Neurosci. Lett. 231, 13 (1997) , (3) M.A. Simmonds et al.: Neuropharmacology 19, 39 (1980) , (4) E. Breuker et al.: Br. J. Pharmacol. 58, 458 (1976)
      InChi
      InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1

      GABAA receptor antagonist.

      SKU: B0239 Category: Phytochemicals
      • Additional information

      Additional information

      Synonyms

      (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one

      Purity

      ≥99% (HPLC)

      Appearance

      Off-white to yellow powder

      CAS-Number

      485-49-4

      Molecular Formula

      C20H17NO6

      Molecular Weight

      367.35

      Identity

      1H-NMR

      Solvents

      chloroform

      Melting Point

      193-197 °C

      Optical Activity

      [α]20/D +126±6°, c = 1% in chloroform

      Smiles

      [H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12

      InChi Key

      IYGYMKDQCDOMRE-ZWKOTPCHSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Hazard statements

      H300, H311, H314, H331, H400

      Precautionary statements

      P261, P264, P273, P280, P301 + P310, P305 + P351 + P338

      GHS Symbol

      GHS05+GHS06+GHS09

      Signal word

      Danger

      RIDADR

      UN1544 6.1

      Transportation

      Excepted Quantities

      References

      (1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997), (2) S.W. Johnson et al.: Neurosci. Lett. 231, 13 (1997), (3) M.A. Simmonds et al.: Neuropharmacology 19, 39 (1980), (4) E. Breuker et al.: Br. J. Pharmacol. 58, 458 (1976)

      InChi

      InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1

      Quantity

      25 mg, 500 mg, 5 g, Bulk

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