- Synonyms: (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one
- Purity: ≥99% (HPLC)
- Appearance: Off-white to yellow powder.
- CAS-Number: 485-49-4
- Molecular Formula: C20H17NO6
- Molecular Weight: 367.35
- Identity: 1H-NMR
- Solvents: chloroform
- Melting Point: 193-197 °C
- Optical Activity: [α]20/D +126±6°, c = 1% in chloroform
- Smiles: [H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12
- InChi: InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1
- InChi Key: IYGYMKDQCDOMRE-ZWKOTPCHSA-N
Available from stock
(+)-Bicuculline
SKU: B0239
Category: Phytochemicals
- Shipping: AMBIENT
- Short Term Storage: +4°C
- Long Term Storage: +4°C
- Handling Advice: Protect from light and moisture.
- Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.
- Description: GABAA receptor antagonist.
- References: (1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997), (2) S.W. Johnson et al.; Neurosci. Lett. 231, 13 (1997), (3) M.A. Simmonds et al.; Neuropharmacology 19, 39 (1980), (4) E. Breuker et al.; Br. J. Pharmacol. 58, 458 (1976)
GABAA receptor antagonist.
Additional information
| Molecular Formula | |
|---|---|
| Identity | 1H-NMR |
| InChi | InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 |
| Availability | 1 |
| CAS-Number | 485-49-4 |
| Handling Advice | Protect from light and moisture. |
| InChi Key | IYGYMKDQCDOMRE-ZWKOTPCHSA-N |
| Appearance | Off-white to yellow powder. |
| Long Term Storage | +4°C |
| Melting Point | 193-197 °C |
| Quantity | 25 mg, 5 g, 500 mg, Bulk |
| Pricetable | |
| Molecular Weight | |
| References | (1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997), (2) S.W. Johnson et al.; Neurosci. Lett. 231, 13 (1997), (3) M.A. Simmonds et al.; Neuropharmacology 19, 39 (1980), (4) E. Breuker et al.; Br. J. Pharmacol. 58, 458 (1976) |
| Shipping | AMBIENT |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Purity | |
| Short Term Storage | +4°C |
| Optical Activity | [α]20/D +126±6°, c = 1% in chloroform |
| Solvents | chloroform |
| Synonyms | (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one |
| Smiles | [H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12 |
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