Available from stock

(+)-Bicuculline

Category: Phytochemicals

Synonyms: (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one; 485-49-4
CAS-Number: C₂₀H₁₇NO₆
Molecular Formula: 367.35
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Hazard statements: H300, H311, H314, H331, H400
Precautionary statements: P261, P264, P273, P280, P301 + P310, P305 + P351 + P338
GHS Symbol: GHS05+GHS06+GHS09
Signal word: Danger
RIDADR: UN1544 6.1
Transportation: Excepted Quantities

Description: GABAA receptor antagonist.
Smiles: [H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12
InChi Key: IYGYMKDQCDOMRE-ZWKOTPCHSA-N
References: (1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997) , (2) S.W. Johnson et al.: Neurosci. Lett. 231, 13 (1997) , (3) M.A. Simmonds et al.: Neuropharmacology 19, 39 (1980) , (4) E. Breuker et al.: Br. J. Pharmacol. 58, 458 (1976)
InChi: InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1

GABAA receptor antagonist.

SKU: B0239 Category: Phytochemicals

Additional information

Synonyms	(6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one
Purity	≥99% (HPLC)
Appearance	Off-white to yellow powder
CAS-Number	485-49-4
Molecular Formula	C20H17NO6
Molecular Weight	367.35
Identity	1H-NMR
Solvents	chloroform
Melting Point	193-197 °C
Optical Activity	[α]20/D +126±6°, c = 1% in chloroform
Smiles	[H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12
InChi Key	IYGYMKDQCDOMRE-ZWKOTPCHSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H300, H311, H314, H331, H400
Precautionary statements	P261, P264, P273, P280, P301 + P310, P305 + P351 + P338
GHS Symbol	GHS05+GHS06+GHS09
Signal word	Danger
RIDADR	UN1544 6.1
Transportation	Excepted Quantities
References	(1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997), (2) S.W. Johnson et al.: Neurosci. Lett. 231, 13 (1997), (3) M.A. Simmonds et al.: Neuropharmacology 19, 39 (1980), (4) E. Breuker et al.: Br. J. Pharmacol. 58, 458 (1976)
InChi	InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1
Quantity	25 mg, 500 mg, 5 g, Bulk