Specifications
- Purity
- ≥99% (HPLC)
- Identity
- 1H-NMR
- Appearance
- Off-white to yellow powder
Properties
- Optical Activity
- [α]20/D +126±6°, c = 1% in chloroform
- Melting Point
- 193-197 °C
- Solvents
- chloroform
Downloads
- Safety Data Sheet
- CDX B0239 MSDS.pdf
Available from stock
(+)-Bicuculline
- SKU
- B0239
Category: Phytochemicals
- Synonyms
- (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one
- 485-49-4
- CAS-Number
- C20H17NO6
- Molecular Formula
- 367.35
- Molecular Weight
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Long Term Storage
- +4°C
- Short Term Storage
- +4°C
- Shipping
- AMBIENT
- Transportation
- Excepted Quantities
- RIDADR
- UN1544 6.1
- Signal word
- Danger
- GHS Symbol
- GHS05+GHS06+GHS09
- Precautionary statements
- P261, P264, P273, P280, P301 + P310, P305 + P351 + P338
- Hazard statements
- H300, H311, H314, H331, H400
- Description
- GABAA receptor antagonist.
- InChi
- InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1
- References
- (1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997) , (2) S.W. Johnson et al.: Neurosci. Lett. 231, 13 (1997) , (3) M.A. Simmonds et al.: Neuropharmacology 19, 39 (1980) , (4) E. Breuker et al.: Br. J. Pharmacol. 58, 458 (1976)
- InChi Key
- IYGYMKDQCDOMRE-ZWKOTPCHSA-N
- Smiles
- [H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12
GABAA receptor antagonist.
Additional information
| Synonyms | (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one |
|---|---|
| Purity | ≥99% (HPLC) |
| Appearance | Off-white to yellow powder |
| CAS-Number | 485-49-4 |
| Molecular Formula | C20H17NO6 |
| Molecular Weight | 367.35 |
| Identity | 1H-NMR |
| Solvents | chloroform |
| Melting Point | 193-197 °C |
| Optical Activity | [α]20/D +126±6°, c = 1% in chloroform |
| Smiles | [H][C@]1(OC(=O)C2=C1C=CC1=C2OCO1)[C@@]1([H])N(C)CCC2=CC3=C(OCO3)C=C12 |
| InChi Key | IYGYMKDQCDOMRE-ZWKOTPCHSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H300, H311, H314, H331, H400 |
| Precautionary statements | P261, P264, P273, P280, P301 + P310, P305 + P351 + P338 |
| GHS Symbol | GHS05+GHS06+GHS09 |
| Signal word | Danger |
| RIDADR | UN1544 6.1 |
| Transportation | Excepted Quantities |
| References | (1) M. Avoli et al. Can. J. Physiol. Pharmacol. 75, 526 (1997), (2) S.W. Johnson et al.: Neurosci. Lett. 231, 13 (1997), (3) M.A. Simmonds et al.: Neuropharmacology 19, 39 (1980), (4) E. Breuker et al.: Br. J. Pharmacol. 58, 458 (1976) |
| InChi | InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 |
| Quantity | 25 mg, 500 mg, 5 g, Bulk |
