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Calcium pantothenate

SKU: C0657

Category: Vitamins

Synonyms: (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt , D-Pantothenic acid hemicalcium salt , Calcium D-pantothenate , Vitamin B5; 137-08-6
CAS-Number: C₉H₁₆NO₅ · ₀.₅Ca
Molecular Formula: 238.27
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98%
Appearance: White to off-white powder
Identity: 1H-NMR

Properties

Solvents: DMSO (44 mg/ml), water (44 mg/ml), ethanol (<1 mg/mL)
Melting Point: 198 - 199 °C
Optical Activity: [α]25/D +25.0° to +28.0°

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Transportation: Not dangerous goods

Description: Calcium pantothenate (Vitamin B5) is a water-soluble vitamin, an essential nutrient required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates and fats. CoA is important in energy metabolism for pyruvate to enter the tricarboxylic acid cycle (TCA cycle) as acetyl-CoA, and for α-ketoglutarate to be transformed to succinyl-CoA in the cycle. CoA is also important in the biosynthesis of many important compounds such as fatty acids, cholesterol, and acetylcholine. CoA is incidentally also required in the formation of ACP, which is also required for fatty acid synthesis in addition to CoA. Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain cereals, legumes, eggs, meat, royal jelly, avocado and yogurt. Only the dextrorotatory (D) isomer possesses biological activity, such as antibacterial or metabolic properties.
Smiles: OCC(C)(C)[C@@H](O)C(NCCC([O-])=O)=O.[Ca+2]
InChi Key: SXRRAEDIIGNDNU-FJXQXJEOSA-M
References: (1) P. Gardner, et al., Food Chem. 68, 471 (2000) , (2) B. Ou, et al., J. Agric. Food Chem. 50, 2772 (2002) , (3) T. Bahorun, et al., J. Sci. Food Agric. 84, 1553 (2004) , (4) W. He, et al., Front. Immunol. 9, 365 (2018) , (5) S. Patassini, et al., Metabolites 9, E113 (2019) , (6) Q. Ma, et al., Am. J. Transl. Res. 11, 5008 (2019)

Calcium pantothenate (Vitamin B5) is a water-soluble vitamin, an essential nutrient required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates and fats. CoA is important in energy metabolism for pyruvate to enter the tricarboxylic acid cycle (TCA cycle) as acetyl-CoA, and for α-ketoglutarate to be transformed to succinyl-CoA in the cycle. CoA is also important in the biosynthesis of many important compounds such as fatty acids, cholesterol, and acetylcholine. CoA is incidentally also required in the formation of ACP, which is also required for fatty acid synthesis in addition to CoA. Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain cereals, legumes, eggs, meat, royal jelly, avocado and yogurt. Only the dextrorotatory (D) isomer possesses biological activity, such as antibacterial or metabolic properties.

SKU: C0657 Category: Vitamins

Additional information

Additional information

Synonyms	(R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, D-Pantothenic acid hemicalcium salt, Calcium D-pantothenate, Vitamin B5
Purity	≥98%
Appearance	White to off-white powder
CAS-Number	137-08-6
Molecular Formula	C9H16NO5 · 0.5Ca
Molecular Weight	238.27
Identity	1H-NMR
Solvents	DMSO (44 mg/ml), water (44 mg/ml), ethanol (<1 mg/mL)
Melting Point	198 – 199 °C
Optical Activity	[α]25/D +25.0° to +28.0°
Smiles	OCC(C)(C)[C@@H](O)C(NCCC([O-])=O)=O.[Ca+2]
InChi Key	SXRRAEDIIGNDNU-FJXQXJEOSA-M
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) P. Gardner, et al., Food Chem. 68, 471 (2000), (2) B. Ou, et al., J. Agric. Food Chem. 50, 2772 (2002), (3) T. Bahorun, et al., J. Sci. Food Agric. 84, 1553 (2004), (4) W. He, et al., Front. Immunol. 9, 365 (2018), (5) S. Patassini, et al., Metabolites 9, E113 (2019), (6) Q. Ma, et al., Am. J. Transl. Res. 11, 5008 (2019)
Quantity	25 g, 100 g, Bulk