Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- Faint to dark yellow powder or crystals
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform
Available from stock
Diclofenac Impurity B
- SKU
- D1228
Category: API's & Intermediates
- Synonyms
- Diclofenac impurity B (PhEur), 2-(2,6-Dichloranilino)-benzaldehyd, N-(2,6-Dichlorphenyl)-anthranilaldehyd
- 22121-58-0
- CAS-Number
- C13H9Cl2NO
- Molecular Formula
- 266.12
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H302 - H413
- Precautionary statements
- P301 + P312 + P330
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Diclofenac Impurity B is a degradation product of and a regulatory impurity in the drug Diclofenac which is a non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat inflammation associated with arthritis and gout as well as other pain or inflammatory disorders. This product can be used as a working standard or secondary analytical reference standard. It can also be used as an organic building block and intermediate for synthesis.
- Smiles
- ClC1=C(NC2=CC=CC=C2C=O)C(Cl)=CC=C1
- InChi Key
- MILOIOYXRHLAAH-UHFFFAOYSA-N
- References
- (1) C. Martinez, et al., Appl. Cat. B Environ. 107, 110 (2011) , (2) X. Cheng, et al., J. Environm. Chem. Eng. 3, 1713 (2015) , (3) M. Azougagh, et al., Ann. Pharm. Fr. 74, 358 (2016) , (4) S. Orlandini, et al., J. Chromatogr. A 1466, 189 (2016) , (5) C. Caprini, et al., J. Pharm. Biomed. Anal. 149, 249 (2018)
- InChi
- InChi=1S/C13H9Cl2NO/c14-10-5-3-6-11(15)13(10)16-12-7-2-1-4-9(12)8-17/h1-8,16H
Diclofenac Impurity B is a degradation product of and a regulatory impurity in the drug Diclofenac which is a non-steroidal anti-inflammatory drug (NSAID) that is clinically used to treat inflammation associated with arthritis and gout as well as other pain or inflammatory disorders. This product can be used as a working standard or secondary analytical reference standard. It can also be used as an organic building block and intermediate for synthesis.
Additional information
| Synonyms | Diclofenac impurity B (PhEur), 2-(2,6-Dichloranilino)-benzaldehyd, N-(2,6-Dichlorphenyl)-anthranilaldehyd |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | Faint to dark yellow powder or crystals |
| CAS-Number | 22121-58-0 |
| Molecular Formula | C13H9Cl2NO |
| Molecular Weight | 266.12 |
| Identity | 1H-NMR |
| Solvents | chloroform |
| Smiles | ClC1=C(NC2=CC=CC=C2C=O)C(Cl)=CC=C1 |
| InChi Key | MILOIOYXRHLAAH-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H302 – H413 |
| Precautionary statements | P301 + P312 + P330 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) C. Martinez, et al., Appl. Cat. B Environ. 107, 110 (2011), (2) X. Cheng, et al., J. Environm. Chem. Eng. 3, 1713 (2015), (3) M. Azougagh, et al., Ann. Pharm. Fr. 74, 358 (2016), (4) S. Orlandini, et al., J. Chromatogr. A 1466, 189 (2016), (5) C. Caprini, et al., J. Pharm. Biomed. Anal. 149, 249 (2018) |
| InChi | InChi=1S/C13H9Cl2NO/c14-10-5-3-6-11(15)13(10)16-12-7-2-1-4-9(12)8-17/h1-8,16H |
| Quantity | 50 mg, Bulk |
